Antifreeze proteins enable organisms to avoid freezing under extreme conditions. The greatest diversity of known antifreeze proteins is in teleost fish and much work has gone into the understanding of these proteins and their applications.
Antifreeze proteins are an exciting model system for the study of protein–surface(ice) interaction. They have served as unique model structures in protein science and they are also useful tools in the study of fish physiology and behavior. Their emergence in some fish species has even provided a rare glimpse of de novo protein evolution in action.
To cover the diverse aspects of fish antifreeze study, a wide spectrum of researchers have been selected to write clear and comprehensive articles on different areas of antifreeze research. This book should be a very useful and informative resource for life science researchers.
Contents:
- Early Research on Proteins from the Antarctic: Antifreeze Glycoproteins (R A Feeney & D T Osuga)
- Physiological Ecology of Antifreeze Proteins — A Northern Perspective (S V Goddard & G L Fletcher)
- Fish Antifreeze Proteins: Functions, Molecular Interactions and Biological Roles (K V Ewart)
- Origins and Evolution of Fish Antifreeze Proteins (C C-H Cheng & A L DeVries)
- The Structure of Fish Antifreeze Proteins (D J Brown & F D Sönnichsen)
- Control of Antifreeze Protein Gene Expression in Winter Flounder (M Miao et al.)
- The Skin-Type Antifreeze Polypeptides: A New Class of Type I AFPs (W-K Low et al.)
- The Interaction of Antifreeze Proteins with Model Membranes and Cells (M M Tomczak & J H Crowe)
- Antifreeze Protein Gene Transfer in Salmonids (W-K Low et al.).
Readership: Undergraduate, graduate students and researchers (both academic and industrial) in biotechnology, molecular & cell biology, and animal physiology.
“The writing is lucid, the approach consistent throughout, last not least because the editors are experts in this field and also because they were able to recruit elaborated contributions from a small group of other leading scientists.”
Archive of Fishery and Marine Research
Dr Vanya Ewart is currently a researcher at the National Research Council Institute for Marine Biosciences, Canada. She also lectures Biochemistry at the Dalhousie University. She has been awarded the following: the Medical Research Council of Canada�s Fellowship with the Department of Biochemistry, University of Toronto and Department of Microbiology and Infectious Diseases, University of Calgary from 1993–1996. She has also contributed to the industrial development on biotechnology in her research in fishes and has lead a team project funded by the Canadian acquaculture and fish processing company, which has successfully developed new scalable processes for the purification of valuable biologicals from fish blood and testing.
Professor HEW Choy Leong is the Head of Department of Biological Sciences at the National University of Singapore and the Deputy Director for the Tropical Marine Science Institute. Some of the awards and honours he has been awarded include the 1972–1974 C H Best Fellowship, Banting & Best Dept of Medical Research, Univ of Toronto; 1980 APICS–Fraser Award, Most Outstanding Young Scientist in Atlantic Provinces of Canada, 1992 Outstanding Achievement Award, Chinese Community Centre of Ontario Incorporated. He has published research papers in major publications such as Biological Chemistry (1998, 2000) and Transgenic Research (1999).