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Pharmaceutical development and medical applications of porphyrin-type macrocycles

TARAK D. MODY

Pharmacyclics, Inc., 995 East Arques Avenue, Sunnyvale, CA 94086, USA

Corresponding author: Pharmacyclics, Inc., 995 East Arques Avenue, Sunnyvale, CA 94086, USA.

https://doi.org/10.1002/(SICI)1099-1409(200006/07)4:4<362::AID-JPP250>3.0.CO;2-ZCited by:73 (Source: Crossref)

Abstract

The current state of pharmaceutical development of porphyrin-type macrocycles in medicine is highlighted. Currently, several porphyrinoid-based drugs are under various stages of development as phototherapeutic agents, X-ray radiation enhancers and boron neutron capture agents. These compounds represent a burgeoning class of pharmacological agents that are potentially useful in an array of treatment areas.

Keywords:

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Vol. 04, No. 04

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Accepted 22 December 1999

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System Upgrade on Tue, May 28th, 2024 at 2am (EDT)

Pharmaceutical development and medical applications of porphyrin-type macrocycles

Abstract

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System Upgrade on Tue, May 28th, 2024 at 2am (EDT)

Pharmaceutical development and medical applications of porphyrin-type macrocycles

Abstract

Recommended

Texaphyrins: a new approach to drug development

Modifying the porphyrin core — a chemist's jigsaw

Phosphorus complexes of porphyrinoid macrocycles

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Water-soluble porphyrin photosensitizers containing electron-withdrawing and electron-donating groups for photodynamic therapy

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Diversity, isomer composition, and design of combinatorial libraries of tetrapyrrole macrocycles

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