Treatment of Lymphatic Filariasis

The following sections are included:

• Introduction

• Tools for Diagnosis and Post-Treatment Follow-up of Filarial Infections

  • Detection of Microfilariae

  • Antigen Detection Assays

  • Filaria-specific Antibodies

  • DNA Detection

  • Ultrasound

  • Other Diagnostic Clues

• Treatment of Lymphatic Filariasis

  • Asymptomatic or Subclinical Lymphatic Filariasis

    • Microfilaria-positive persons

    • Microfilaria-negative adult worm carriers

  • Acute Manifestations of Lymphatic Filariasis

    • Acute filarial adenolymphangitis (AFL)

    • Acute dermatolymphangioadenitis (ADLA)

  • Chronic Manifestations of Lymphatic Filariasis

    • Lymphoedema

  • Urogenital Manifestations of Lymphatic Filariasis

    • Lymphoedema and elephantiasis

    • Lymph scrotum (acquired lymphangioma)

    • Hydrocoele

    • Chylocoele

    • Chyluria

    • Adenopathy

  • Tropical Pulmonary Eosinophilia

• Antifilarial Chemotherapy

  • Diethylcarbamazine (DEC)

    • Microfilaricidal and macrofilaricidal efficacy

    • Side effects and adverse reactions

    • Dosage

    • Effect of DEC on filaria-associated pathology

  • Ivermectin

  • Other Drugs and Drug Combinations

• Community-Based Treatment of Lymphatic Filariasis

• Treatment of Lymphatic Filariasis — Conclusions

• References