Progress in Vaccine Development
The following sections are included:
Rationale for Vaccine Development
Potential Vaccination Approaches
Anti-infection Vaccines
Antifecundity Vaccines
Antipathology Vaccine
Transmission-Blocking Vaccine
Insights from Clinical Studies
Natural and Naturally Acquired Resistance to Infection
Resistance to Reinfection Following Treatment
Preliminary Immune Correlate Studies with Defined Antigens
Points to Consider for Vaccine Trials
Measures of Safety and Efficacy
Use of Vaccines in Control Programs
Testing an Antipathology Vaccine
Practical Issues in Vaccine Development
Caveats and Conclusions
References