Regulation of mRNA Translation and Stability in Iron Metabolism: Is there a Redox Switch?

The following sections are included:

• Summary

• Iron Homeostasis

• Iron Regulatory Proteins and Feedback Regulation of Iron

• Other Targets of Iron Regulatory Proteins

• Regulation of IRE Binding Activity of IRP-1 by Iron

• Regulation of IRP-2 Activity by Iron

• Do IRP-1 and IRP-2 have Similar of Different Functions?

• Modulation of IRP-1 and IRP-2 by Nitric Oxide

• Activation of IRP-1 by Hydrogen Peroxide

• Regulation of IRP-1 by Hypoxia

• Conclusions

• References