Neoadjuvant/Adjuvant/Chemoprevention Therapy and Tumor Downstaging
The following sections are included:
Introduction
Neoadjuvant/Adjuvant/Chemoprevention Therapy in Liver Resection for HCC
Neoadjuvant transarterial chemoembolization (TACE)
Adjuvant regional chemotherapy with or without embolization
Adjuvant regional therapy
Adjuvant regional and systemic therapy
Neoadjuvant plus adjuvant regional therapy
Adjuvant systemic chemotherapy
Adjuvant transarterial radioembolization (TARE)
Adjuvant immunotherapy
Chemoprevention with vitamin analog therapy after curative liver resection
Neoadjuvant/Adjuvant Therapy in Liver Transplantation for HCC
Neoadjuvant TACE
Neoadjuvant local ablative therapy
Neoadjuvant multimodality therapy
Neoadjuvant/Adjuvant systemic chemotherapy
Salvage Surgery After Tumor Downstaging of Advanced HCC
Indication and prerequisites for salvage surgery and tumor downstaging
Rationale for salvage surgery after successful tumor downstaging
Results of salvage surgery after tumor downstaging
Tumor downstaging with TACE
Tumor downstaging with TAC
Tumor downstaging with multimodality therapy
Challenges of tumor downstaging
Prognosis and survival
References