European Structural Proteomics — A Perspective

The following sections are included:

• Introduction

• Bioinformatics and LIMS

  • Target Selection and Construct Design

    • Strasbourg

    • Oxford

  • Wet Lab LIMS

• Automation of Cloning and Expression Screening: Increasing Target Throughput

  • Expression Vectors and Screening Technologies

• Eukaryotic Expression Technologies

• Protein Characterization

• HTP Crystallization, Imaging and Crystal Handling

• NMR Spectroscopy

• X-ray Diffraction Data Collection: Automation for HTP Samples

• Crystallographic Structure Determination

• Structure Annotation

• Summary of Structural Results

• Spine2, Specialist European Programs and the European Outlook

• Conclusions

• References