FUNCTIONAL GENOMICS: A PLATFORM FOR THE DISCOVERY OF NEW THERAPIES

Functional genomics can be described as scientific and technological approaches which are being applied to bridge genomic research with the discovery and development of disease-relevant therapeutic targets. These scientific approaches can offer significant opportunities in the search for causal and disease modifying therapies to better treat society's most outstanding medical needs. The use of functional genomic approaches is demonstrated in our recent efforts to elucidate cellular events leading to tumor cell cycle arrest in response to the inhibition of histone deacetylase, an important regulator of gene transcription.