Twins Studies and Myopia

Twins provide a unique resource with which to study the influence of genetic and environmental factors on the development of myopia. In this chapter we review some of the methodological approaches that have been used in twin cohorts to quantitate the extent of involvement of genes in myopia and its underlying determinants such as axial length, anterior chamber depth, and corneal curvature. The use of twins to study the association of myopia with other factors such as birth weight, body stature, and personality will also be discussed.