Viral DNA Polymerases

The following sections are included:

• Bacteriophage T4 DNA Polymerase

• Bacteriophage T7 DNA Polymerase

• HSV-1 DNA Polymerase

• Protein Primed DNA Replication: Adenoviruses and Bacteriophage ϕ29

  • Adenovirus DNA Polymerase

  • Bacteriophage ϕ29 DNA Polymerase

• African Swine Virus DNA Polymerase

• RNA-Dependent DNA Synthesis: Reverse Transcriptases

  • HIV-1 Reverse Transcriptase

    • The retro-transcription reaction

    • Structural features of HIV-1 reverse transcriptase

    • Enzymatic features of HIV-1 reverse transcriptase

    • The RNase H activity of HIV-1 reverse transcriptase

  • Other Retroviral Reverse Transcriptases

    • HIV-2 reverse transcriptase

    • Murine Leukemia Virus (MLV) reverse transcriptase

    • Equine Infectious Anemia Virus (EIAV) reverse transcriptase

    • Feline Immunodeficiency Virus (FIV) reverse transcriptase

    • Mouse Mammary Tumor Virus (MMTV) reverse transcriptase

  • Reverse Transcriptase Activity of Mobile Genetic Elements: The Retrotransposons

    • Saccharomyces cerevisiae Ty reverse transcriptase

    • Schizosaccharomyces pombe Tf1 reverse transcriptase

    • Bombyx mori R2 reverse transcriptase

  • Hepadnavirus Reverse Transcriptase

• Chapter Summary

• References