Chapter 6: Cortical Depression
The following sections are included:
News and Views
Summary
Introduction
LTD in mammalian central nervous system
Frequency-dependent relationship for inducing LTD
LTD in ACC pyramidal neurons
Requirement of NMDA receptor activation and postsynaptic calcium
NR2A- vs. NR2B-containing NMDA receptors are required for the induction of LTD
NMDA receptor-independent form of LTD
Postsynaptic expression of LTD
Genetic studies of LTD
LTD in other pain-related cortical areas
Functional implication for cortical LTD
Conclusion
References