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FUNCTIONAL ANNOTATION OF INTRINSICALLY DISORDERED DOMAINS BY THEIR AMINO ACID CONTENT USING IDD NAVIGATOR

    https://doi.org/10.1142/9789814366496_0016Cited by:0 (Source: Crossref)
    Abstract:

    The following sections are included:

    • Introduction

    • Methodology

      • Preparation of IDD dataset

      • Similarity scores

        • Similarity score based on Euclidean distance

        • BLAST score

      • Pfam domain and Gene Ontology term prediction

      • Evaluation of function prediction

      • Web server

    • Results and Discussion

      • IDD Navigator Function prediction

      • Comparing different methods in IDD Navigator

      • Function prediction for IDD clusters

      • Case Studies

        • GRA15 from T. gondii

        • Cyclon from M. musculus

        • STIM1 from M. musculus

        • ROP16 from T. gondii

    • Conclusions

    • Acknowledgements

    • References