Uniform Design and Quadratic Polynomial Regression Analysis Applied on the Optimization of Compatibility Study in Traditional Chinese Formula

Compound recipe was the important form in traditional Chinese medicine. A formula is mainly composed of more than two herbs along with application of the single herb. At present, statistics tools were used to optimize the dose or proportion of formula. Here we showed a method based on uniform design and quadratic polynomial regression for the dose and proportion analysis in GeGenQingLian Decoction(GGQLD).The result obtained the different indicators reflected the different principal drug, the different indicators appeared the distinct mechanism of GGQLD in treating the ulcerative colitis(UC).