ALTERATION OF HEAVY METAL CONCENTRATION IN IRRADIATED SARCOMA IN VIVO

Alterations of heavy metal concentration in inoculated Sarcoma -180 after irradiation by 6MeV electron beam at the doses of 5Gy were evaluated in vivo in BALB/c mice, by Particle Induced X -ray Emission (PIXE).

Analysis was performed for K, Cl, S, Fe, Zn and Cu. In the irradiation of 5Gy, the concentration of K and Cl have revealed the fast incremment at 1 hour after irradiattion and the fast decremment after that time. As for the S, Fe, Cu and Zn, their concentrations have revealed the fast incremment at 1 hour after irradiattion and the slow decremment from 1 hour after irradiation (except for slow increment from 1 hour to 1 day after).