The particle induced X-ray emission analysis is applied to mark (or to localize) a cancer lesion from its benign environment in animal experiments. As a photosensitiser, we have used hematoporphyrin derivative (HPD) and in order to make HPD visible to PIXE, we synthesize HPD with rare earth metals to form lanthanide-HPD to enhance the localizing efficiency tremendously and PIXE is used as a straightforward detection method to find the successfulness of the synthesis. In theory, this approach can be used to probe carcinogenesis at cell levels. To increase the cure effects of lanthanide-HPD, we add ZYX to enhance the pharmaceutical effectiveness. ZYX, our code name for a group of drugs and chemicals, is mostly of the Chinese herb extraxctions but some has different origin. We explain the present approach with a specific experiment, Dysprosium-HPD (Dy-HPD) as a localizer, and conclude this article with some comments and perspectives.

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