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SYNTHESIS AND CHARACTERIZATION OF THE ANTIMICROBIAL 4-AMINO-DECYLPYRIDINIUM BROMIDE CATIONIC SURFACTANT

PARAG MADAAN

Department of Oil and Paint Technology, Harcourt Butler Technological Institute, Kanpur 208002, India

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and

V. K. TYAGI

Department of Oil and Paint Technology, Harcourt Butler Technological Institute, Kanpur 208002, India

Corresponding author.

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https://doi.org/10.1142/S0218625X08011743Cited by:6 (Source: Crossref)

Abstract

4-Amino-decylpyridinium bromide (ADPBr), an antimicrobial surface active agent, was synthesized by quaternization of 4-aminopyridine (AP) with decyl bromide (DBr). The reaction was carried out at 1:1.2 molar ratio of reactants (4-aminopyridine and decyl bromide, respectively) at 200°C for 10 min. The maximum yield of the product was 74.6%. The structure of the synthesized product was characterized by using modern analytical techniques, such as FT-IR, ¹H NMR, and ¹³C NMR. The antimicrobial activity of the salt was evaluated with minimum inhibition concentration method and showed good activity against gram-negative bacteria. The MIC of the salt was found to be 600 ppm for 2 × 10⁴ CFU/mL of E. coli.

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