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NUMERICAL SIMULATION OF APPARENT DENSITY EVOLUTION OF TRABECULAR BONE UNDER FATIGUE LOADING: EFFECT OF BONE INITIAL PROPERTIES

Laboratoire des Energies Renouvelables et, Matériaux Avancés (LERMA), Ecole Supérieure de, l’Ingénierie de l’Energie, Université Internationale, de Rabat, Rocade Rabat-Salé, 11100, Rabat-Sala El Jadida, Maroc

E-mail Address: abdelwahed.barkaoui@uir.ac.ma

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RABEB BEN KAHLA

Laboratoire de Systèmes et de Mécanique, Appliquée (Lasmap-EPT), Ecole Polytechnique de Tunis, Université de Carthage, 2078 La Marsa, Tunisie

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TAREK MERZOUKI

Laboratoire Ingénierie des Systèmes de Versailles, Université de Versailles St Quentin en Yvelines, 10 avenue de l’Europe, 78140 Velizy, France

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, and

RIDHA HAMBLI

Laboratoire Prisme, EA4229, Ecole d’Ingénieurs, Polytech Orléans, Université d’Orléans, 8 Rue Léonard de Vinci, 45072 Orléans, France

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https://doi.org/10.1142/S0219519419500416Cited by:11 (Source: Crossref)

Abstract

Bone remodeling is a physiological phenomenon coupling resorption and formation processes that are mainly mediated by osteoclasts and osteoblasts, in response to mechanical stimuli transduced by osteocytes to biochemical signals activating the bone multicellular unit. Under normal loading conditions, bone resorption and formation are balanced by a homeostasis process. When bone is subjected to overstress, microdamaging occurs, which induces a modification of the structural integrity and microarchitecture. This has drawn significant attention to the mechanical properties of bone. In this context, the current study has been carried out with the aim of numerically investigating the impact of the mechanical properties on the remodeling process of the trabecular bone under cyclic loading, highlighting the effects of different values of the mineral density and the Young’s modulus. This was performed using a mechanobiological model, coupling mechanical and biological approaches, allowing to numerically simulate the effect of the selected parameters for a 20-year-period of cyclic loading for 2D and 3D models of a human femur head. The current work is an explorative numerical study, and the obtained results revealed the changes in the overall stiffness of the bone according to the mechanical properties.

Keywords:

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