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A NOVEL METHOD TO PREPARE CROSSLINKED POLYETHYLENEIMINE HOLLOW NANOSPHERES

Engineering Research Center of Biomaterials, Sichuan University, National Engineering Research Center for Biomaterials, Chengdu 610064, China

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Jun-xiao Yang

Engineering Research Center of Biomaterials, Sichuan University, National Engineering Research Center for Biomaterials, Chengdu 610064, China

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Bin He

Engineering Research Center of Biomaterials, Sichuan University, National Engineering Research Center for Biomaterials, Chengdu 610064, China

Corresponding author.

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, and

Zhong-wei Gu

Engineering Research Center of Biomaterials, Sichuan University, National Engineering Research Center for Biomaterials, Chengdu 610064, China

Corresponding author.

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Abstract

A novel method to prepare crosslinked polyethyleneimine (CPEI) hollow nanospheres was reported. Uniform silica nanospheres were used as templates, 3-aminopropyl trimethoxysilane (APS) was immobilized on the surface of silica nanospheres as couple agent. Aziridine was initiated ring-opening polymerization with the amino groups in APS to form polyethyleneimine (PEI) shell layer. 1,4-Butanediol diacrylate was utilized to crosslink PEI polymeric shell. The silica nanospheres in core were etched by hydrofluoric acid to obtain hollow CPEI nanospheres. The hollow nanospheres were characterized by X-ray photoelectron spectroscopy (XPS), transmission electron microscopy (TEM), and thermogravimetric analysis (TGA).

This work was financially supported by the National Basic Research Program of China (National 973 program, No. 2005 CB623903).

Keywords:

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