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Hyaluronic Acid-Modified Hollow Glass Beads Used for Cell Sorting with High Efficiency
https://doi.org/10.1142/S1793292024501340Cited by:0 (Source: Crossref)
Abstract
It is of great significance to sort specific types of cells through a fast and efficient technology in biomedical research and clinical applications. In this study, commercial hollow glass beads were modified with 3-aminopropyltriethoxysilane (ATPES) and hyaluronic acid (HA) sequentially, which can capture HeLa cells with nearly 100% efficiency within 10min. The beads can specifically recognize and sort HeLa cells from a cell coculture of HeLa and L-929 depending on their strong buoyancy and good affinity with cancer cells. The job provides a facile, quick and low-cost cell sorting method, which has potential application in the fields of specific and efficient cell isolation.
