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Parameter identification through mode isolation for reaction–diffusion systems on arbitrary geometries

Laura Murphy

http://orcid.org/0000-0002-2945-5039

School of Mathematical and Physical Sciences, University of Sussex, Department of Mathematics, Brighton BN1 9QH, UK

E-mail Address: L.R.Murphy@sussex.ac.uk

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Chandrasekhar Venkataraman

School of Mathematics and Statistics, University of St Andrews, St Andrews, UK

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, and

Anotida Madzvamuse

School of Mathematical and Physical Sciences, University of Sussex, Department of Mathematics, Brighton BN1 9QH, UK

E-mail Address: A.Madzvamuse@sussex.ac.uk

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https://doi.org/10.1142/S1793524518500535Cited by:6 (Source: Crossref)

Abstract

We present a computational framework for isolating spatial patterns arising in the steady states of reaction–diffusion systems. Such systems have been used to model many natural phenomena in areas such as developmental and cancer biology, cell motility and material science. In many of these applications, often one is interested in identifying parameters which will lead to a particular pattern for a given reaction–diffusion model. To attempt to answer this, we compute eigenpairs of the Laplacian on a variety of domains and use linear stability analysis to determine parameter values for the system that will lead to spatially inhomogeneous steady states whose patterns correspond to particular eigenfunctions. This method has previously been used on domains and surfaces where the eigenvalues and eigenfunctions are found analytically in closed form. Our contribution to this methodology is that we numerically compute eigenpairs on arbitrary domains and surfaces. Here we present examples and demonstrate that mode isolation is straightforward especially for low eigenvalues. Additionally, we show that in some cases the inhomogeneous steady state can be a linear combination of eigenfunctions. Finally, we show an example suggesting that pattern formation is robust on similar surfaces in cases that the surface either has or does not have a boundary.

Keywords:

AMSC: 35K55, 37C75, 65M60

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Vol. 11, No. 04

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History

Received 1 June 2017

Accepted 14 March 2018

Published: 3 May 2018

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This is an Open Access article published by World Scientific Publishing Company. It is distributed under the terms of the Creative Commons Attribution 4.0 (CC-BY) License. Further distribution of this work is permitted, provided the original work is properly cited.

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Parameter identification through mode isolation for reaction–diffusion systems on arbitrary geometries

Abstract

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