Special Issue on Bio-Inspired Nanotechnology; Guest Editors: Susan Hong Zhou and Yubing Xie — Review ArticlesNo Access

GOLD NANOPARTICLES-BASED BIOSENSORS FOR BIOMEDICAL APPLICATION

JING ZHAO

Laboratory of Biosensing Technology, School of Life Sciences, Shanghai University, Shanghai 200444, P. R. China

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BING BO

Department of Oncology, The First Affiliated, Hospital of Nanjing Medical University, Nanjing 210029, P. R. China

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YONG-MEI YIN

Department of Oncology, The First Affiliated, Hospital of Nanjing Medical University, Nanjing 210029, P. R. China

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, and

GEN-XI LI

Laboratory of Biosensing Technology, School of Life Sciences, Shanghai University, Shanghai 200444, P. R. China

Department of Biochemistry and State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210093, P. R. China

Corresponding author.

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https://doi.org/10.1142/S1793984412300087Cited by:6 (Source: Crossref)

Abstract

Gold nanoparticles are the most extensively studied nanomaterials for biomedical application due to their unique properties, such as rapid and simple synthesis, large surface area, strong adsorption ability and facile conjugation to various biomolecules. The remarkable photophysical properties of gold nanoparticles have provided plenty of opportunities for the preparation of gold nanoparticles-based optical biosensors, while the excellent biocompatibility, conductivity, catalytic properties and large surface-to-volume ratio have facilitated the application of gold nanoparticles in the construction of electrochemical biosensors. In this review, we mainly detail the gold nanoparticles-based optical and electrochemical biosensors for biomedical application in the recent two years, which have exhibited greatly enhanced analytical performances in the detection of DNA, proteins and some important small molecules.

Keywords:

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