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Core-Shell Structured Theranostics

Qingwen Guan

Department of Mechanical Engineering, Faculty of Engineering, The University of Hong Kong, Pokfulam Road, Hong Kong

Department of Mechanical and Energy Engineering, Southern University of Science and Technology, Shenzhen, P. R. China

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and

Min Wang

Department of Mechanical Engineering, Faculty of Engineering, The University of Hong Kong, Pokfulam Road, Hong Kong

E-mail Address: memwang@hku.hk

Corresponding author.

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https://doi.org/10.1142/S179398442141004XCited by:2 (Source: Crossref)

This article is part of the issue:

Guest Editors: Min Wang, Chong Wang and Qilong Zhao

Abstract

Cancer threatens the life and well-being of human beings. Millions of newly diagnosed cancer cases and a large number of deaths caused by cancer are reported each year in the world. Early detection and effective treatment are key to reduce cancer mortality, which can be potentially realized by using “theranostics”. Theranostics are a group of hybrid nanoparticles that perform in cancer patients to provide both diagnostic and therapeutic functions through a single nano-sized structure. In particular, core-shell structured theranostics have shown unique physicochemical properties, allowing them to facilitate molecular/cell targeting, bio-imaging, and drug delivery functions. This review, therefore, aims to present and discuss the recent development of research on core-shell structured theranostics. Specifically, it focuses on core-shell structured theranostics made of metals, silica and polymers. Different aspects, such as synthesis and structure, of core-shell structured theranostics are discussed in this review. This review helps readers to have a good understanding of the design and fabrication of core-shell structured theranostics.

Keywords:

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