Case ReportNo Access

Neurolymphomatosis of the Ulnar Nerve Presenting as Cubital Tunnel Syndrome: A Case Report

Yeong Chang LEE

Department of Orthopedic Surgery, Wonkwang University Hospital, Iksan, South Korea

Search for more papers by this author

Seon Kwan JUHNG

Department of radiology, Wonkwang University Hospital, Iksan, South Korea

Search for more papers by this author

, and

Hong Je KANG

Department of Orthopedic Surgery, Wonkwang University Hospital, Iksan, South Korea

E-mail Address: KangHongJe@hanmail.net

Correspondence to: Hong Je Kang, Department of Orthopedic Surgery, School of Medicine, Wonkwang University Hospital 895, Muwang-Ro, Iksan 54538, Korea. Tel: +82-63-859-1360, Fax: +82-63-852-9329.

Search for more papers by this author

https://doi.org/10.1142/S242483552272016XCited by:0 (Source: Crossref)

Abstract

Lymphoma is a malignant tumour of the lymphatic system. Neurolymphomatosis occurs when lymphoma cells invade the peripheral nervous system (PNS). Neurolymphomatosis has been reported involving the sciatic nerve, nerve roots and within the axilla and the upper arm. It can cause nerve dysfunction depending on the involved nerve. Neurolymphomatosis involving the ulnar nerve is rare. We report a patient with neurolymphomatosis of the ulnar nerve around the elbow that presented with features of cubital tunnel syndrome. A high index of suspicion is necessary in patients with cubital tunnel syndrome that present with uncommon symptoms such as sudden onset, rapid progression and/or severe pain.

Level of Evidence: Level V (Therapeutic)

Keywords:

REFERENCES

1. Magee RB, Phalen GS. Tardy ulnar palsy. Am J Surg. October 1949;78(4):470–474. https://doi.org/10.1016/0002-9610(49)90205-6. Crossref, Google Scholar
2. Jung YH, Song WS, Park SR. Neurolymphomatosis involving antebrachial cutaneous nerve. J Korean Orthop Assoc. 2016;51(4):345–349. https://doi.org/10.4055/jkoa.2016.51.4.345 Crossref, Google Scholar
3. Currie S, Henson RA. Neurological syndromes in the reticuloses. Brain. 1971;94(2):307–320. https://doi.org/10.1093/brain/94.2.307. Crossref, Google Scholar
4. Kelly JJ, Karcher DS. Lymphoma and peripheral neuropathy: a clinical review. Muscle Nerve. March 2005;31(3):301–313. https://doi.org/10.1002/mus.20163. Crossref, Google Scholar
5. Sita-Alb L, Sobec R, Fodor L. Primary B lymphoma tumor of the ulnar nerve. Case report. Med Pharm Rep. July 2019;92(3):303–307. https://doi.org/10.15386/mpr-1315. Crossref, Google Scholar
6. Gan HK, Azad A, Cher L, Mitchell PL. Neurolymphomatosis: diagnosis, management, and outcomes in patients treated with rituximab. Neuro Oncol. February 2010;12(2):212–215. https://doi.org/10.1093/neuonc/nop021. Crossref, Google Scholar
7. Foo TL, Yak R, Puhaindran ME. Peripheral nerve lymphomatosis. J Hand Surg Asian Pac Vol. March, 2017;22(1):104–107. https://doi.org/10.1142/S0218810417720042 Link, Google Scholar
8. Suleman F, Velleman M. Cubital tunnel syndrome: a report of two cases. South African Journal of Radiology. 2012;16(2):77–78. https://doi.org/10.4102/sajr.v16i2.314 Crossref, Google Scholar
9. Byun WM, Park WK, Park BH, Ahn SH, Hwang MS, Chang JC. Guillain-Barré syndrome: MR imaging findings of the spine in eight patients. Radiology. July 1998;208(1):137–141. https://doi.org/10.1148/radiology.208.1.9646804. Crossref, Google Scholar
10. Lagarde S, Tabouret E, Matta M, et al.. Primary neurolymphomatosis diagnosis and treatment: a retrospective study. J Neurol Sci. July 15, 2014;342(1–2):178–181. https://doi.org/10.1016/j.jns.2014.04.030. Crossref, Google Scholar