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Paternal Age Does Not Influence the Outcomes of Assisted Reproduction in Donor Oocyte Cycles

Oasis Center for Reproductive Medicine, Near NATCO Pharma, Banjara Hills Road No. 2, Hyderabad 500034, Andhra Pradesh, India

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Saniya Laheri

Molecular and Cellular Biology Laboratory, National Institute for Research in Reproductive Health (ICMR), J. M. Street, Parel, Mumbai 400012, Maharashtra, India

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, and

M Krishna Chaitanya

Oasis Center for Reproductive Medicine, Near NATCO Pharma, Banjara Hills Road No. 2, Hyderabad 500034, Andhra Pradesh, India

E-mail Address: krishna@oasisindia.in

Corresponding author.

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https://doi.org/10.1142/S2661318220500073Cited by:0 (Source: Crossref)

Abstract

Purpose: To study effect of paternal age on pregnancy outcomes of intracytoplasmic sperm injections (ICSI).

Methods: The present study is a retrospective analysis of 153 ICSI cycles on donor oocytes. The effect of paternal age on fertilization rates, implantation rates, total pregnancy rates, number of miscarriages and live births were analyzed.

Results: 1422 donor oocytes were injected with sperm from 153 men. Linear regression analysis revealed no association between paternal age (28-54 years) and fertilization rate. No association was found between the embryo quality and paternal age. Of the 359 embryos transferred, linear regression analysis revealed no association between paternal age and implantation rate. After correcting for maternal age, binary logistic regression analysis revealed no association between total pregnancy rates (B = 0.943, CI 0.861-1.033, P = 0.205), live birth rates (B = 1.018, CI 0.896-1.158, P = 0.562) and miscarriage rates (B = 0.944, CI 0.866-1.029, P = 0.193) and paternal age.

Conclusion: Paternal age does not seem to influence outcomes in assisted reproduction.

Keywords:

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Vol. 02, No. 02

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History

Received 3 March 2020

Accepted 30 March 2020

Published: 16 May 2020

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This is an Open Access article published by World Scientific Publishing Company. It is distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 (CC BY-NC-ND) License which permits use, distribution and reproduction, provided that the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Paternal Age Does Not Influence the Outcomes of Assisted Reproduction in Donor Oocyte Cycles

Abstract

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