Basal Factors Recognize Promoters and Assemble the Pre-Initiation Transcription Complexes

The following sections are included:

• σ Factors Recruit Bacterial RNA Polymerases to Different Promoters and Assist Transcript Initiation

• Simple Beginnings: The Archaeal TATA-Binding Protein (TBP)-TFB-RNAP Initiation Complex

• Eukaryotic RNAP_II Promoters: TATA-Boxes, Initiator Elements and TBP/TBP-Associated Factors Responsible for Sequence-Specific Recognition

• Recruitment of RNAP_II/TFIIF

• Promoter Melting, Transcript Initiation and the Role of TFIIE and TFIIH

• Re-initiation and Recycling of Basal Factors

• Basal Factors Reorganize Promoter Topology

• The RNAP_II Holoenzyme

• Conclusions

• References