Appearing on the Horizon: Medical Applications Focusing on Transcriptional Control Mechanisms

The following sections are included:

• The Need for Drugs Affecting Gene Expression Patterns

• Strategies for Identifying Drugs Interfering with Gene-specific Transcriptional Regulators

• Reprogramming Transcription Patterns I: Drugs that Control Expression of Genes In Vivo

• Reprogramming Transcription Patterns II: Drug-Mediated Activation of Alternate Members of Multigene Families

• Nucleic Acid-Based Gene-Specific Therapeutic Agents

• Drugs That Control Gene Transcription by Indirect Means

• Conclusions

• References