Factors Influencing Organophosphate Toxicity in Humans

The following sections are included:

• Introduction

• Route of Exposure and Absorption

  • Oral

  • Dermal

  • Inhalation

• Dose

• Distribution

• Metabolism

  • A-esterases

  • Carboxylesterases (including B-esterases)

  • Fluorohydrolases

  • Amidases

  • Microsomal Oxygenases

  • Conjugation

• Tissue binding

• Elimination

• Alterations in Metabolism

• Racemic Mixtures

• Concluding Remarks

• References