BIOLOGICAL INTERPRETATION OF QUANTITATIVE PET BRAIN DATA
The variety of available positron emission tomography (PET) radiotracers and the ability of providing quantitative estimates of radiotracer concentrations make PET an invaluable tool in the in-vivo investigation of biological processes. Mathematical descriptions of the processes under investigation are used to extract relevant kinetic parameters from the time course of radioactivity concentrations. Such kinetic parameters can provide a quantitative description of both, the characteristics of a particular process, and its changes due to various disease states.