Gene Therapy for the Heart

The following sections are included:

• Introduction - Rationale for Gene Therapy for Heart Disease, a Clinician's Perspective

• The “Limited Option” Patient with Severe Angina

• Therapeutic Angiogenesis – Is this Feasible?

• Which Gene Product to Choose?

• Modes of Gene Delivery

• Results of Randomized Controlled Clinical Trials of Gene Therapy

• Prior Shortcomings and Future Directions

• References

• Glossary of Terms

• Review Questions