BRAIN DEVELOPMENT DURING NORMAL GROWTH

The following sections are included:

• HYPERPLASTIC GROWTH OF THE BRAIN

  • Species Differences

  • Structural Differences

  • Grey and White Matter of the Developing Brain

  • Growth of Different Cell Types

  • Control of Cellular Proliferation

    • Genetic control

    • Polyamines and cell proliferation

  • Neurogenesis

  • Gliogenesis

  • Neuronal Death and Nervous System Development

  • Regeneration of Brain Cells

• HYPERTROPHIC DEVELOPMENT OF THE BRAIN

  • Brain Proteins during Development

  • Brain Lipids during Development

    • Cholesterol

    • Cholesterol esters

    • Phospholipids

    • Cerebroside and sulphatide

    • Gangliosides

    • Lipids of the grey and white matter

• MYELIN COMPOSITION DURING BRAIN MATURATION

  • Myelin Lipids

  • Myelin Proteins

  • Lipid-protein Associations in Developing Myelin

  • Involvement of cAMP in Myelinogenesis

  • Nerve Activity and Myelin Stability

• SYNAPTIC DEVELOPMENT

  • Increases in Dendritic Arborization and Axon Density

  • Nerve Activity and Synaptic Refinement

  • Mechanism of Synaptogenesis

  • Orchestration at the Synapse

  • Involvement of cAMP in Synaptogenesis

  • Synaptic Regeneration

  • Involvement of cAMP in Nerve Regeneration

• METABOLISM OF THE DEVELOPING BRAIN

  • Metabolism of Lipids

  • Metabolism of Amino Acids and Proteins

  • Energy Metabolism