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Single nucleotide polymorphism genotyping using DNA sequencing on multiwalled carbon nanotubes monolayer by CNT-plasmon resonance

H. V. Grushevskaya

Physics Department, Belarusian State University, 4 Nezalezhnasti Ave., 220030 Minsk, Belarus

E-mail Address: grushevskaja@bsu.by

Corresponding author.

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N. G. Krylova

Physics Department, Belarusian State University, 4 Nezalezhnasti Ave., 220030 Minsk, Belarus

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I. V. Lipnevich

Physics Department, Belarusian State University, 4 Nezalezhnasti Ave., 220030 Minsk, Belarus

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V. P. Egorova

Belarusian State Pedagogical University, 18 Sovetskaya Str., 220030 Minsk, Belarus

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, and

A. S. Babenka

N.N. Alexandrov National Cancer Centre of Belarus, 223040 Lesnoy, Minsk District, Belarus

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https://doi.org/10.1142/S0217979218400337Cited by:7 (Source: Crossref)

This article is part of the issue:

SPECIAL ISSUE — Electron Correlation in Superconductivity and Nanostructures; Guest Editor: Sergei Kruchinin

Abstract

DNA-nanosensor based on multiwalled carbon nanotubes (MWCNTs) decorated by nanocyclic thiophene-pyrrole complexes of octahedral high-spin Fe has been proposed for high-performance sensing of DNA-hybridization utilizing a surface-enhanced spin-dependent CNT-plasmon resonance. This DNA-nanosensor operates on screening and quenching effects at Raman scattering of light in duplexes DNA-probe/DNA-target at complementary pairing of nucleotides in DNA. Single nucleotide polymorphism (SNP) genotyping has been successfully performed for DNA samples from healthy and cancer-suffering donors.

Keywords:

PACS: 81.05.U, 82.47.Rs, 87.85.fk

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