BRIEF REPORTNo Access

Co₃O₄ Nanoparticles as a Noninvasive Electrochemical Sensor for Glucose Detection in Saliva

Mei Wang

School of Computer and Communication Engineering, Zhengzhou University of Light Industry, Zhengzhou 450000, P. R. China

E-mail Address: pettyinchina1314@163.com

Corresponding author.

Search for more papers by this author

Fang Liu

School of Computer and Communication Engineering, Zhengzhou University of Light Industry, Zhengzhou 450000, P. R. China

Search for more papers by this author

Zhifeng Zhang

College of Software Engineering, Zhengzhou University of Light Industry, Zhengzhou 450000, P. R. China

Search for more papers by this author

Erchao Meng

State Laboratory of Surface and Interface Science and Technology, Zhengzhou University of Light Industry, Zhengzhou 450000, P. R. China

Search for more papers by this author

Feilong Gong

State Laboratory of Surface and Interface Science and Technology, Zhengzhou University of Light Industry, Zhengzhou 450000, P. R. China

Search for more papers by this author

, and

Feng Li

State Laboratory of Surface and Interface Science and Technology, Zhengzhou University of Light Industry, Zhengzhou 450000, P. R. China

Search for more papers by this author

https://doi.org/10.1142/S1793292021500090Cited by:13 (Source: Crossref)

Abstract

A new noninvasive glucose sensor is developed based on Co₃O₄ particles (Co₃O₄ NPs), which are synthesized by a single-step hydrothermal method with uniform structure and size. The electrochemical measurements reveal that the device exhibits outstanding performance for glucose detection, achieving a maximal sensitivity of 2495.79 $μ$ A mM $^{- 1}$ cm $^{- 2}$ with a high $R^{2}$ of 0.99575, a ultra-low detection limit of 9.3nM with a signal-to-noise of 3 and linear range up to 3mM. The noninvasive glucose sensor can respond swiftly and selectively due to the high electrocatalytic activity of Co₃O₄ NPs. The sensor also shows its high sensitivity and selectivity in detecting glucose levels in human blood serum and saliva sample, confirming the application potential of Co₃O₄ NPs in noninvasive detection of glucose.

Keywords:

References

1. P. Balasubramanian, M. Annalakshmi, S.-M. Chen and T.-W. Chen , Sens. Actuators B, Chem. 299, 126974 (2019). Web of Science, Google Scholar
2. P. Chakraborty, S. Dhar, N. Deka, K. Debnath and S. P. Mondal , Sens. Actuators B, Chem. 302, 127134 (2020). Web of Science, Google Scholar
3. J. Chen, X. Zhu, Y. Ju, B. Ma, C. Zhao and H. Liu , Sens. Actuators B, Chem. 285, 56 (2019). Web of Science, Google Scholar
4. V. E. Coyle, A. E. Kandjani, M. R. Field, P. Hartley, M. Chen, Y. M. Sabri and S. K. Bhargava , Biosens. Bioelectron. 141, 111479 (2019). Web of Science, Google Scholar
5. Y. J. Lee, K. S. Eom, K.-S. Shin, J. Y. Kang and S. H. Lee , Sens. Actuators B, Chem. 271, 73 (2018). Web of Science, Google Scholar
6. H.-Q. Xia, H. Tang, B. Zhou, Y. Li, X. Zhang, Z. Shi, L. Deng, R. Song, L. Li, Z. Zhang and J. Zhou , Sens. Actuators B, Chem. 312, 127962 (2020). Web of Science, Google Scholar
7. H. Yoon, J. Nah, H. Kim, S. Ko, M. Sharifuzzaman, S. C. Barman, X. Xuan, J. Kim and J. Y. Park , Sens. Actuators B, Chem. 311, 127866 (2020). Web of Science, Google Scholar
8. A. Romeo, T. S. Moya, G. Leung, R. Gabriel, Villa and S. Sánchez , Appl. Mater. Today 10, 133 (2018). Web of Science, Google Scholar
9. M. Janyasupab, C.-W. Liu, N. Chanlek, S. Chio-Srichan, C. Promptmas and W. Surareungchai , Sens. Actuators B, Chem. 286, 550 (2019). Web of Science, Google Scholar
10. D. Tankasala and J. C. Linnes , Transl. Res. 213, 1 (2019). Web of Science, Google Scholar
11. P. Chakraborty, S. Dhar, K. Debnath, T. Majumder and S. P. Mondal , Sens. Actuators B, Chem. 283, 776 (2019). Web of Science, Google Scholar
12. N. I. Chandrasekaran and M. Matheswaran , Sens. Actuators B, Chem. 288, 188 (2019). Web of Science, Google Scholar
13. E. Rafatmah and B. Hemmateenejad , Sens. Actuators B, Chem. 304, 127335 (2020). Web of Science, Google Scholar
14. A. Scandurra, F. Ruffino, S. Sanzaro and M. G. Grimaldi , Sens. Actuators B, Chem. 301, 127113 (2019). Web of Science, Google Scholar
15. J. Chen, H. Yin, J. Zhou, L. Wang, J. Gong, Z. Ji and Q. Nie , J. Electron. Mater. 49, 4754 (2020). Web of Science, Google Scholar
16. Y.-S. Hsieh, P.-W. Wang, C. Y. Li, S.-J. Hsieh, C.-Y. Wang, D.-W. Chou, N.-F. Wang and M.-P. Houng , Sens. Mater. 32, 1843 (2020). Web of Science, Google Scholar
17. S. Malhotra, Y. Tang and P. K. Varshney , Anal. Bioanal. Electrochem. 10, 699 (2018). Web of Science, Google Scholar
18. X. Wang, X. Xia, X. Zhang, W. Meng, C. Yuan and M. Guo , Mat. Sci. Eng. C-Mater. Biol. Appl. 80, 174 (2017). Web of Science, Google Scholar
19. S. Rajendran, D. Manoj, K. Raju, D. D. Dionysiou, M. Naushad, F. Gracia, L. Cornejo, M. A. Gracia-Pinilla and T. Ahamad , Sens. Actuators B, Chem. 264, 27 (2018). Web of Science, Google Scholar
20. R. Madhuvilakku, R. Mariappan, S. Alagar and S. Piraman , Anal. Chim. Acta 1042, 93 (2018). Web of Science, Google Scholar
21. J. Zhu, H. Yin, J. Gong, M. S. H. Al-Furjan and Q. Nie , J. Alloys Compd. 748, 145 (2018). Web of Science, Google Scholar
22. P. Yang, X. Wang, C.-Y. Ge, X. Fu, X. Y. Liu, H. Chai, X. Guo, H.-C. Yao, Y. X. Zhang and K. Chen , Appl. Surf. Sci. 494, 484 (2019). Web of Science, Google Scholar
23. S. Cheng, S. DelaCruz, C. Chen, Z. Tang, T. Shi, C. Carraro and R. Maboudian , Sens. Actuators B, Chem. 298, 126860 (2019). Web of Science, Google Scholar
24. Y. Gao, Q. Yu, Y. Du, M. Yang, L. Gao, S. Rao, Z. Yang, Q. Lan and Z. Yang , J. Electroanal. Chem. 838, 41 (2019). Web of Science, Google Scholar
25. M. Harry, M. Chowdhury, F. Cummings and C. J. Arendse , Sens. Biosensing Res. 23, 100262 (2019). Google Scholar
26. X. Lin, Y. Wang, M. Zou, T. Lan and Y. Ni , Chin. Chem. Lett. 30, 1157 (2019). Web of Science, Google Scholar
27. S. Pourbeyram, J. Abdollahpour and M. Soltanpour , Mat. Sci. Eng. C-Mater. Biol. Appl. 94, 850 (2019). Web of Science, Google Scholar
28. J. Zhu, W. Tu, H. Pan, H. Zhang, B. Liu, Y. Cheng, Z. Deng and H. Zhang , Acs Nano 14, 5780 (2020). Web of Science, Google Scholar
29. W. Xu, J. Chen, M. Yu, Y. Zeng, Y. Long, X. Lu and Y. Tong, ( 4, 10779, 2016). J. Mater. Chem. A 8, 17827 (2020). Google Scholar
30. Z. Yang, X. Bai, C. Qi and J. You , J. Electrochem. Soc. 167, 027518 (2020). Web of Science, Google Scholar
31. Dhanjai, P. Balla, A. Sinha, L. Wu, X. Lu, D. Tan and J. Chen , Talanta 203, 112 (2019). Web of Science, Google Scholar
32. J. Luo, J. Wu, Z. Liu, Z. Li and L. Deng , J. Nanomater. 2019, 8346251 (2019). Google Scholar
33. L. T. Hoa, J. S. Chung and S. H. Hur , Sens. Actuators B, Chem. 223, 76 (2016). Web of Science, Google Scholar
34. K. Khun, Z. H. Ibupoto, X. Liu, V. Beni and M. Willander , Mater. Sci. Eng. B, Adv. Funct. Solid-State Mater. 194, 94 (2015). Web of Science, Google Scholar
35. L. Wang, Y. Zhang, Y. Xie, J. Yu, H. Yang, L. Miao and Y. Song , Appl. Surf. Sci. 402, 47 (2017). Web of Science, Google Scholar
36. H. Xu, C. Xia, S. Wang, F. Han, M. K. Akbari, Z. Hai and S. Zhuiykov , Sens. Actuators B, Chem. 267, 93 (2018). Web of Science, Google Scholar
37. S. Mondal, R. Madhuri and P. K. Sharma , J. Mater. Chem. C 5, 6497 (2017). Google Scholar
38. L. Tian, G. He, Y. Cai, S. Wu, Y. Su, H. Yan, C. Yang, Y. Chen and L. Li , Nanotechnology 29, 075502 (2018). Web of Science, Google Scholar
39. X. Zhang, Y. Xu, H. Liu, W. Zhao, A. Ming and F. Wei , Rsc Adv. 10, 2191 (2020). Web of Science, Google Scholar
40. Z. Jin, L. P. Wang, Y. Zhang, J. Fan, M. H. Liao, X. F. Wang and Y. Ding , J. Nanoparticle Res. 21, 115 (2019). Web of Science, Google Scholar
41. L. Q. Zhang, Z. F. Gao, C. Liu, Y. H. Zhang, Z. Q. Tu, X. P. Yang, F. Yang, Z. Wen, L. P. Zhu, R. Liu, Y. F. Li and L. S. Cui , J. Mater. Chem. A 3, 2794 (2015). Google Scholar
42. C. Su, L. Zhang, Y. Han, X. Chen, S. Wang, M. Zeng, N. Hu, Y. Su, Z. Zhou, H. Wei and Z. Yang , Sens. Actuators B, Chem. 288, 699 (2019). Web of Science, Google Scholar
43. J. Lu, H. Zhang, S. Li, S. Guo, L. Shen, T. Zhou, H. Zhong, L. Wu, Q. Meng and Y. Zhang , Inorg. Chem. 59, 3152 (2020). Web of Science, Google Scholar
44. M. Wang, M. Shi, E. Meng, F. Gong and F. Li , Micro Nano Lett. 15, 191 (2020). Web of Science, Google Scholar
45. S. Fan, M. Zhao, L. Ding, J. Liang, J. Chen, Y. Li and S. Chen , J. Electroanal. Chem. 775, 52 (2016). Web of Science, Google Scholar
46. L. Kang, D. He, L. Bie and P. Jiang , Sens. Actuators B, Chem. 220, 888 (2015). Web of Science, Google Scholar
47. J. Xu, F. Li, D. Wang, M. H. Nawaz, Q. An, D. Han, and L. Niu , Biosens. Bioelectron. 123, 25 (2019). Web of Science, Google Scholar
48. M. A. Yassin, B. K. Shrestha, R. Ahmad, S. Shrestha, C. H. Park and C. S. Kim , J. Ind. Eng. Chem. 73, 106 (2019). Web of Science, Google Scholar