Primary Cell Lines and Stem Cells
The following sections are included:
Introduction
Human Embryonic Stem Cells
Maintenance of ESCs
Induced Pluripotent Stem Cells (iPS Cells)
Adult Tissue-Derived Stem Cells
Mesenchymal stem cells (MSCs)
Defining MSCs: Isolation, identification, and selection
MSC Niche: The Bone Marrow (BM) microenvironment
In vivo and in vitro capabilities
MSC self-renewal
Immune function
Multilineage differentiation potential
Osteogenesis
Chondrogenesis
Adipogenesis
Tenogenesis
Myogenesis
Therapeutic potential: Immune regulation, tissue repair, and gene therapy
Limitations of MSCs
Conclusion
References