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We dwell upon the physicist's conception of 'life' since Schrödinger and Wigner through to the modern-day language of living systems in the light of quantum information. We discuss some basic features of a living system such as ordinary replication and evolution in terms of quantum bio-information. We also discuss the principle of no-culling of living replicas. We show that in a collection of identical species there can be no entanglement between one of the mutated copies and the rest of the species in a closed universe. Even though these discussions revolve around 'artificial life' they may still be applicable in real biological systems under suitable conditions.