Aging is associated with numerous physiologic and psychosocial changes and with increased needs for medical care. Older adults are usually affected by two or more chronic diseases; are ill longer; have longer hospital stays; and hence, greater physical, mental and financial burdens. Complementary and alternative medicines (CAM), especially in the form of herbal medicines and botanical dietary supplements, are options that are being increasingly used by adults, including elderly consumers over 60 years of age, to treat or prevent a wide array of ailments such as chronic pain, arthritis, high cholesterol, insomnia, anxiety, Alzheimer disease, dementia, benign prostatic hyperplasia, and cardiovascular diseases. There are currently thousands of traditional medicines (TM) and other CAM herbal products available as such therapeutic agents worldwide. Yet, of the nearly 2000 herbal medicines listed in the Cochrane Controlled Trials Register as of June 2009, most of the clinical trials focus on a single plant herbal or phytomedicine. Hence, in this review, we will concentrate on single herb products that have been documented to have some clinical evidence of efficacy and/or safety for the treatment of diseases associated with aging. Space limitations, however, will not allow us to discuss every herbal product useful for this group of the population. In this review, the following herbs and their potential medical uses will be presented as examples of herbal medicine of potential relevance to the aging population. The examples presented are Boswellia (potentially useful for the management of arthritis, bronchial asthma, Crohn's disease, and ulcerative colitis), Echinacea (treatment and prevention of upper respiratory infections), Ginkgo (treatment and prevention of dementia), Ginseng (adaptogen for the maintenance and restoration of health, among other chronic conditions), Hawthorn (potential cardiovascular adjunct), Huperzia (Alzheimer's disease), Pygeum (Benign Prostatic Hyperplasia), and Saw Palmetto (Benign Prostatic Hyperplasia).