This research investigates the performance of ABS P400 parts under compressive loading. These ABS P400 parts are fabricated by fused deposition modeling (FDM) process using omnidirectional printing. The effects of three critical parameters, raster angle (A), air gap (B), and raster width (C), each at three different levels, were analyzed on three different performance measures, i.e. total deformation up to failure (TD) measured in %, maximum energy (ME) in MJ/m3 and break energy (BE) in MJ/m3. Results of experimentations were analyzed using analysis of variance (ANOVA), perturbation curve and 3D surface plots. The research established the anisotropic nature, durability and less brittleness of the FDM fabricated ABSP400 part, which leads to lower strength and also influence the energy absorbing behavior while deformation under compression. Complex relationships were exhibited between the chosen parameters and studied measures. It was also observed that TD is noticeable due to less brittleness of ABS P400 however, TD and BE vary in a contradictory fashion with changes in process parameters. The models were validated using normality plots. Multi-objective optimization was done using the desirability approach to determine the optimal combination of FDM process parameters for optimum responses. The desirability result showed that the optimized input parameter is A=60∘,B=0.002mm, and C=0.477mm which yield maximized optimum responses as TD=47.94%, ME=1.6×106MJ/m3, and BE=2.13×107MJ/m3. The work not only reflects the effect of three FDM parameters on the total deformation up to failure (TD in %) but, in addition, energy absorption behavior of FDM parts under compression is also investigated. The study on the behavior of energy at ultimate stress or ultimate load and breaking stress or breaking load were rarely investigated in earlier research which reflects the novelty of our research.