Modern gait analysis results in large quantities of correlated data. A current challenge in the field is the development of appropriate data analysis techniques for the representation and interpretation of these data. Knee osteoarthritis is a common debilitating disease of the musculoskeletal system that has been the focus of many gait studies in recent years. Various data analysis techniques have been used to extract pathological information from gait data in these studies. The following review discusses the successes and limitations of many of these analysis techniques in the attempt to understand the biomechanics of knee osteoarthritis.