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In this paper, combined with physiological anatomy knowledge, the complete finite element model of L3–L4 lumbosacral segment of human lumbar was established by using the 3D graphic of human spine L3–L4 segment, which is obtained by image diagnosis technique (CT scan). This model includes the sections of the bones, the intervertebral disc and the anterior ligament, the posterior ligament, the ligamentum flavum, the fibrous ring and other major spine attached soft tissue. Then the finite element model meshing and the material properties of the corresponding part setting were done on the constructed model, and different loads and boundary conditions were imposed to simulate the displacement and stress and strain nephogram of the normal model and intervertebral disc herniation, senile degeneration and other models in different movement states. And the effectiveness of model data is verified by analyzing its biomechanical properties. The biomechanical properties of the spine obtained by the finite element method can be used to provide biomechanical basis for the diagnosis and treatment of intervertebral disc herniation and degeneration.