Corneal injuries in pets cause severe suffering and vision impairment, creating significant challenges in the field of veterinary medicine. It is important to understand that the cornea lacks the inherent capability to regenerate itself through the administration of substances such as hyaluronic acid or antibiotics, which are commonly utilized by veterinarians for managing edema and infections in animals. It has been shown that platelet rich fibrin extract (PRFE) is effective in healing both deep corneal ulcers and superficial keratitis. In this case report, the use of PRFE in dogs and cats which showed promising results.