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The theory of cometary panspermia is reviewed in relation to evidence from astronomy, biology and recent studies of meteorites. The spectroscopic signatures in interstellar material within our galaxy and in external galaxies that have been known for many years most plausibly represent evidence for the detritus of life existing on a cosmic scale. Such spectral features discovered in galaxies of high redshift points to life arising at a very early stage in the history of the Universe. Evidence of fossils of microscopic life forms in meteorites that have been discussed over several decades, and augmented recently with new data, reaffirms the case for cometary panspermia.