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The article is about Biopolis Shared Facilities. It is an overview of the purpose-built resource that provides research support to the Biopolis community. It mentions the facilities, equipment and technologies that it offers to the Biopolis community.

A Crisis in the Development of Antibiotics.

Bacterial Culture and Anti-microbial Susceptibility Testing – their Use in Guiding Therapy.

Epidemiology and Impact of Multi-Drug Resistant Gram Negative Infections in Critically Ill Patients in Asia.

Antibiotics and Resistance in Ocular Infections – Indian Perspective.

China Unveils World-Class Biotech Ambitions.

Chinese Scientists Awarded Cancer Research Prize.

BGI Researchers Uncover Extensive RNA Editing in Human Transcriptome.

Johns Hopkins Commences New China STEM Program.

Father of Hybrid Rice Conferred 2011 Mahathir Science Award.

Personalized Medicine Receives Boost in China.

GeneNews & Shanghai Biochip to Establish First Sentinel Centre for Personalized Medicine.

SINANO Invents New Microfluidic Chip for Bacterial Culture.

MALAYSIA — Veolia expands presence in East Malaysia.

SINGAPORE — Syneron Dental Lasers signs distribution agreement with Healthcare Solutions & Services Pte Ltd.

SINGAPORE — Fujitsu advances healthcare innovation in collaboration with National University of Singapore.

SINGAPORE — Clearbridge BioMedics makes a big impact at the 2012 Asian Innovation Awards.

SINGAPORE — TauRx Pharmaceuticals receives $111.8m commitment from Genting to prepare for Market Leadership in Alzheimer's.

THAILAND — Key Phase II HIV/HCV trial has commenced in Bangkok.

AUSTRALIA — Hatchtech mechanism of action data and safety study published.

AUSTRALIA — Power to you: carbon nanotube muscles are going strong.

EUROPE — GE Healthcare Life Sciences opens new £3 million laboratories for cell science.

EUROPE — AstraZeneca announces Phase III results from naloxegol pivotal trials.

EUROPE — ACADIA's pimavanserin sees Phase III success.

EUROPE — Big Pharma is doing more for access to medicine in developing countries.

EUROPE — CAVATAK™ bladder cancer – positive preliminary data.

EUROPE — Avita Medical initiates European trial in the management of chronic lower limb ulcers.

NORTH AMERICA — FEI unveils broad correlative microscopy solution set for cell biologists.

NORTH AMERICA — A single dose of Medicago's H5N1 VLP vaccine protects against additional pandemic flu strains in a preclinical study.

NORTH AMERICA — Biologics and stem cell research boost the cell culture market.

Cognoptix licenses AD detection technology.

3D cell culture firm Reinnervate and specialist Oncology CRO Oncotest GmbH enter collaboration agreement.

Medicago awarded contract from the U.S. Department of Defence.

Clinical Network Services acquires New Zealand partner BELTAS' business assets.

VABIOTECH licenses cell-based Japanese encephalitis technology from Inviragen.

University of Illinois licenses novel anti-cancer therapies to StemPar Sciences.

Adimab announces new discovery collaboration with Kyowa Hakko Kirin.

Priaxon enters collaboration with GSK on protein-protein-interactions.

Lantheus Medical Imaging and FUJIFILM RI Pharma renew long-term license and distribution agreement.

Malaysian Bio-XCell Sdn Bhd seals a deal exceeding US$35 (~RM107m) with Agila Biotech Sdn Bhd during BioPharma Asia 2013.

Nagasaki University and Astellas launch collaborative research for screening new anti-dengue virus drugs for neglected tropical diseases.

Eurofins collaborates with AB SCIEX and Phenomenex to improve analysis of animal feed.

Biolife Science $5m ASX listing to progress stomach & breast cancer vaccine.

Naz Haji appointed Chief Information Officer, Quintiles Asia markets.

Roche and BioLamina start collaboration to develop novel cell culture systems.

Social anxiety disorder (SAD) is a form of anxiety disorder that is often under-diagnosed. Commonly masked as shyness or introversion, many who are suffering from symptoms of SAD do not receive treatment. The onset of SAD is in childhood and/or early adolescence, and often accompanied by a wide range of comorbidities, including anxiety and depression. As a result, those who suffer from SAD are functionally impaired, likely under-achieve in work and school, and may possibly have unfulfilling relationships. The paper, firstly, reviews various available literature on SAD, its clinical symptoms, prevalence, onset, comorbidities and possible etiologies. Secondly, a case study, constructed based on the authors’ counselling experiences and observations, highlights the common behavioural patterns, cognitive distortions and emotional distress of clients undergoing SAD. Possible perpetuating factors and circumstances further provide a relevant and realistic perspective of the disorder within the Singapore context. Finally, through a review of the unique cultures of three countries, namely Singapore, India and Indonesia, the paper highlights the effects of social competitiveness, social appearance, social hierarchy, shame, technology and social media on the development and perpetuation of SAD amongst children, adolescents and females.

This is a conceptual paper that tries to highlight, articulate and think about the relationship of public relations (PR) with culture, and examines how Saudi Arabian traditional cultural practices, such as wasta and karam, influence how PR functions in this area. While PR in the Middle East is currently still developing, its present state is affected by confusion as to what PR means and what it should do in a company. Researchers have examined what determines the state of PR in this area by examining the economic development of the countries and the relationship between PR practitioners and journalists. Existing research has, however, chosen to look at Arab PR through a Western lens, which means they have examined the state of PR in this area by Western standards of PR and have not taken into consideration Arab culture. The paper will examine how the elements and cultural differences complicate the understanding of PR practice in Saudi Arabia and therefore what questions need to be asked to be able to clarify these things at a theoretical level, but also to be able to look at the practice in analytical terms.

Student counselling in schools is an area that is well established in both developing and developed countries around the world, and has been made available to a wide range of ages (i.e. 5–18 years old) (Harris, 2013). In addition, while the many benefits of student counselling have been widely researched and documented, the problems and obstacles encountered by student counsellors has received less attention. This research aims to combine a brief review of the literature, with the researcher's own 16 years of professional experience of student counselling in Saudi schools, in order to provide a critical account of Saudi student counselling practices. The research shows that cultural, social and financial barriers and challenges may be stopping student counselling practices from developing effectively in Saudi Arabia. It puts forward ways in which student counselling practices might be improved in order to help children and young people in schools across Saudi Arabia.

Chondrocytes in the growth plate undergo a relatively linear differentiation process. The progression of a chondrocyte from the proliferative stage to the hypertrophic stage is governed by complex interactions with the extracellular matrix within which it resides. A network of peptides, ion channels, and second messengers affects the transcription of certain genes that are ultimately translated into peptides which control cellular activity. Much effort has been invested into replicating this environment under in vitro conditions. It has been found that the three-dimensional (3D) cell culture is a more accurate representation of the in vivo environment in comparison to the traditional monolayer culture. It has also been found that a variety of stimuli may be used to induce the proliferation and differentiation of chondrocytes; one such stimulus is the mechanical stimulation of chondrocytes embedded in a 3D Gelfoam sponge. Chondrocytes are obtained from the chicken sternum. After the cells are cultured and cyclically loaded, mRNA levels of various mechanosensitive genes are quantified by real-time reverse transcription-polymerase chain reaction (RT-PCR). Mechanical stimulation has been shown to upregulate the expression of type X collagen mRNA in early hypertrophic chondrocytes. The entire process, beginning with the obtainment of chondrocytes and ending with the quantification and interpretation of gene expression, is detailed in the following chapter.

Effects of porous hydroxyapatite granules (HAGs) on osteogenesis were examined in vitro using cells from adult rabbit femurs. Cultures in the space of 30-600 μm between glass plates with two-dimensionally arranged HAGs on the horizontal bottom glass surface induced thin insular tissue formation within 2 weeks. It was induced earlier and more than that without HAGs. Von Kossa staining-positive tissues were found at 1-2 weeks after their formation, suggesting their mineralization. No cells or several cells in monolayer were included within some of them. Several grew quadrate tissues. Similar thin tissues were formed in inclined and rotated glass tubes with three-dimensionally arranged HAGs. They were almost irregular in shape. By contrast, little extracellular matrix deposition and no mineralization were seen in the spaces over 600 μm and under 30 μm between the glasses with HAGs. These results suggest that osteoblastic cells from adult femurs form mineralized quadrate tissues with or without embedded cells on the horizontal glass in the space of 30-600 μm, while mechanical loading without system induces irregular-shaped tissue formation. Porous HAGs in the space seem to accelerate extracellular matrix accumulation and its mineralization.