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  • articleNo Access

    Research Findings

      Pre-Germinated Brown Rice May Possibly Benefit Alzheimer’s Patients.

      Genetically Engineered Plants for Preventing Diabetes.

      Gene Therapy — A Novel Treatment for Alzheimer’s.

      Potential New Treatment for Stroke and Neurodegenerative Diseases.

    • articleNo Access

      EYE ON CHINA

        Institute of Biological Chemistry researchers find new protein-DNA interaction.

        Medicago to receive up to US$12 million.

        INEX inks partnership with BGI for new non-invasive prenatal test.

        China emerging as 'major player' for pharmaceuticals.

        Possible cure for dementia found by Taiwan researchers.

        BGI@CHOP Joint Genome Center to offer clinical next-generation sequencing services.

        Biologists at Academia Sinica develops a new molecular strategy to suppress Hepatitis C virus replication.

        Molecular cloning, characterization, and expression analysis of genes encoding Gibberellin 20-Oxidase in Dasypyrumvillosum dwarf mutant.

      • articleNo Access

        BIOBOARD

          AUSTRALIA – HIV trial validates novel drug mechanism.

          SINGAPORE – IBN engineered artificial human livers for drug testing and discovery.

          SINGAPORE – Scientists at A*STAR's Genome Institute of Singapore catch evolving germs and cancer cells early.

          SINGAPORE – DocDoc and Chatter Buzz Media enter strategic partnership to launch Asia's first healthcare Content Marketing Network.

          UNITED STATES – New method developed to expand blood stem cells for bone marrow transplant.

          UNITED STATES – Fibrocell/UCLA study on human skin cells yields promising results.

          UNITED STATES – Metal stents are effective treatment for blocked bile ducts.

          UNITED STATES – Pain drug may prevent preemie lung damage.

          UNITED STATES – Gene x3 helps corn grow in acidic soil.

          UNITED STATES – Cancer Genetics selected by Gilead Sciences, Inc. to provide clinical trial services for chronic lymphocytic leukemia.

          UNITED KINGDOM – DaTSCAN™ SPECT imaging demonstrates impact on the diagnosis of patients with clinically uncertain dementia.

          AFRICA – Failing vaccine strategies need to be revamped.

          AFRICA – RegeneCure's membrane implant shows 40% accelerated healing time of severe bone fractures.

        • articleNo Access

          FEATURES

            Is Aging a Risk Factor for Cancer?

            Adverse Effects of Substance Abuse on Aging: Implication of Brain Cell Injury

            Diabetes and the Elderly

            The Necessity for Early Therapeutic Interventions in Dementia: The Role of Neurosteroids

          • articleNo Access

            BIOBOARD

              INDIA – Ozone eating away Indian crop yields.

              INDIA – Polio shots better than oral drops, says study.

              JAPAN – Natural protein in rice helps keep arsenic out in grains.

              THE PHILIPPINES – Philippines adopts inactivated polio vaccine strategy.

              SINGAPORE – A*STAR's Institute of Microelectronics and Singapore Biomicro to develop a first-of-its-kind, implantable wireless blood glucose monitoring sensor device.

              THAILAND – Ebola-affected countries face new threat: food crisis.

              THAILAND – Fending off dengue with insecticide-treated uniforms.

              AFRICA – New test to combat major cause of preventable blindness in Africa.

              BANGLADESH – Arsenic linked to lung cancer in Bangladesh.

              EUROPE – Human-milk-oligosaccharides can protect against noroviruses.

              UNITED STATES – Researchers discover possible cause of common dementia.

              UNITED STATES – Improved mouse model may accelerate research on potential Ebola vaccines and treatments.

              UNITED STATES – New device yields close-up look at metastasis.

              UNITED STATES – Scientists research ways to use an organism's own pathway to synthesize potential therapeutics.

              RESEARCH HIGHLIGHTS – Quality issues in herbal medicine clinical trials.

            • articleNo Access

              BIOBOARD

                SINGAPORE – VIVA Foundation and NUS Launches $10 Million Cancer Research Centre for Childhood Leukaemia.

                SINGAPORE – Discovery Paves the Way for Potential Genetics-Guided Precision Medicine for Paediatric Leukaemia Patients.

                SINGAPORE – Partnership between Sony and Alder Hey Children's Hospital Drives Innovation in Children's Healthcare.

                UNITED STATES – UGA Researchers Make Link between Genetics and Aging.

                UNITED STATES – Latin Dancing may Have Health Benefits for Older Adults.

                UNITED STATES – Interferon Not Beneficial for Most Stage III Melanoma.

                UNITED STATES – Dissecting the Animal Diet, Past and Present.

                UNITED STATES – Water Conservation Important to Many; Only Some Take Action.

                UNITED KINGDOM – Innova Biosciences Introduces New LATEX One-Step Conjugation Kits.

                UNITED KINGDOM – New Understanding of the Mechanism of Neurodegeneration Leads to a Novel Approach to Treatment for Alzheimer's Disease.

                TAIWAN – Breakthrough in Homogeneous Antibody Development and a New Generation of Glycoarray Technology.

                TAIWAN – Increasing Protein Synthesis by Leucine Ameliorates Synaptopathy Caused by Dementia, ALS and Autism.

              • articleNo Access

                BIOBOARD

                  SINGAPORE – NUS Study: Daily Consumption of Tea Protects the Elderly from Cognitive Decline.

                  SINGAPORE – Singapore Researchers Use Patients’ Stem Cells to Test for Side Effects of Drugs – Discovery Brings Doctors Closer to Personalized Medicine.

                  UNITED STATES – Diabetes in Your DNA? Scientists Zero in on the Genetic Signature of Risk.

                  UNITED STATES – Super Resolution Imaging Helps Determine a Stem Cell’s Future.

                  UNITED STATES – Wearable Biosensors Can Tell You When to See the Doctor.

                  AUSTRALIA – PromarkerD Predictive Diagnostics for DKD to Roll-out in Asia.

                  JAPAN – Enrollment Commences in Phase III Clinical Study of Eisai’s BACE Inhibitor Elenbecestat in Early Alzheimer’s Disease in Japan.

                • articleNo Access

                  COLUMNS

                    Brain aging in ASEAN.

                    What value-based healthcare means for Asia.

                    Improve healthcare access to tackle Asia’s healthcare challenge.

                  • articleNo Access

                    FEATURES

                      Emerging treatments for spinal cord damage.

                      Dementia, Alzheimer’s, Parkinson’s – Confusions, myths and tips.

                      An update on Alzheimer’s disease.

                      Integration of Traditional Chinese medicine and Western medicine in cancer treatment.

                      TCM’s integration into modern health system.

                    • articleNo Access

                      An Experimental Study on Evaluating Alzheimer’s Disease Features using Data Mining Techniques

                      Alzheimer’s disease (AD) predominantly affects the elderly population with symptoms including, but not limited to, cognitive impairment and memory loss. Predicting AD and mild cognitive impairment (MCI) can lengthen the lifespan of patients and help them to access necessary medical resources. One potential approach to achieve an early diagnosis of AD is to use data mining techniques which explore various characteristic traits related to MCI, cognitively normal (CN), and AD subjects to build classifiers that reveal important contributors to the disease. These classifiers are used by physicians during the AD diagnostic process in a clinical evaluation. In this research, we compare between different data mining algorithms through empirical data approach to deal with the AD diagnosis. Experimental evaluation, using attribute selection methods, and classifiers from rule induction and other classification techniques have been conducted on data from the Alzheimer’s Disease Neuroimaging Initiative (ADNI-MERGE). The results illustrate the good classification performance of classifiers with rules in predicting AD.

                    • chapterNo Access

                      A Preliminary Study on the Obstacles of Dementia Examination for Retired Elderly Based on Service Experience Survey - Mainly on MMSE

                      An aging society leads to the growth of the mentally retarded population. According to the statistics of the Taiwan Association of Dementia in 2019, nearly half (34) of the 74 mentally retarded people were not diagnosed with dementia when they suffered financial losses. More than 90% (65) were not declared to be assisted or supervised. As most of the family members of patients do not understand the symptoms of dementia, and the patients themselves are unwilling to admit and refuse to be tested for dementia. In this study, a tool for examining the medication payment for dementia in Taiwan was used to test the mini-mental state examination (MMSE) for retired elderly people. The potential design requirements are proposed by contextual observation: (1) changing the type of dementia test, such as taking board games, and integrating MMSE questions into the game can reduce the subjects’ vigilance, (2) changing the presentation and interaction mode of topics, using the agricultural products (space), festivals (time), and celebration activities (space) in Taiwan to test the topics of space, time, memory, calculation and drawing, and interacting and testing them in a non-verbal way to increase understanding and interest, (3) using nostalgic elements to connect the elderly with memory, and (4) examining the living environment at home and promoting family interaction.