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  • articleNo Access

    DIAGNOSIS OF BRAIN REGIONS DISORDERS CAUSED BY DIVING USING INTELLIGENT MODEL BASED ON CELLULAR NEURAL NETWORK

    Diver’s disease is a complication that the human body suffers from after being in a high-pressure space and then quickly entering a low-pressure space. These pressures are very harmful for the tissues of the body, especially for the brain. Decompression sickness occurs when nitrogen bubbles up in the bloodstream, caused by staying underwater too long or surfacing too quickly. Decompression sickness symptoms usually appear with a delay after diving. By processing electroencephalography, information about neurophysiological disorders can be extracted precisely. Since the diagnosis of divers’ diseases has not been dealt with using a unique model, this paper deals with the diagnosis of brain abnormalities caused by diving. In this paper, an intelligent model using the electroencephalography of divers will be presented to diagnose the brain disorders. The proposed model based on the brain function can show the connections of the divers’ brain regions using cellular neural networks. First, the effective features are extracted from the signals, and then based on the proposed architecture based on the brain, the differences in the brain connections of divers compared to non-divers are expressed. The obtained results show that there are differences in intra-regional connections of some brain regions of divers including T7, T8, O1 and O2 (p < 0.05) compared to nondivers.

  • articleNo Access

    Role of Alternative Food in Controlling Chaotic Dynamics in a Predator–Prey Model with Disease in the Predator

    It is generally, but not always, accepted that alternative food plays a stabilizing role in predator–prey interaction. Parasites, on the other hand, have the ability to change both the qualitative and quantitative dynamics of its host population. In recent times, researchers are showing growing interest in formulating models that integrate both the ecological and epidemiological aspects. The present paper deals with the effect of alternative food on a predator–prey system with disease in the predator population. We show that the system, in the absence of alternative food, exhibits different dynamics viz. stable coexistence, limit cycle oscillations, period-doubling bifurcation and chaos when infection rate is gradually increased. However, when predator consumes alternative food coupled with its focal prey, the system returns to regular oscillatory state from chaotic state through period-halving bifurcations. Our study shows that alternative food may have larger impact on the community structure and may increase population persistence.

  • articleNo Access

    GLOBAL SPREAD OF INFECTIOUS DISEASES

    We develop simple models for the global spread of infectious diseases, emphasizing human mobility via air travel and the variation of public health infrastructure from region to region. We derive formulas relating the total and peak number of infections in two countries to the rate of travel between them and their respective epidemiological parameters.

  • articleNo Access

    EFFECT OF PARASITIC INFECTION IN THE LESLIE–GOWER PREDATOR–PREY MODEL

    The Leslie–Gower predator–prey model with logistic growth in prey is here modified to include an SI parasitic infection affecting the prey population only. Thresholds are identified for the predator population to survive, and the conditions for the disease to die out naturally are given. The behavior of the system around each equilibrium is investigated, showing that the disease incidence may have a relevant influence on the dynamics of complex ecosytems, assuming at times the role of a biological control parameter.

  • articleNo Access

    A MINIMAL MODEL FOR ECOEPIDEMICS WITH GROUP DEFENSE

    The new idea of group defense as recently introduced by the author in the context of two interacting populations is in this paper applied to communities subject also to a disease. The system is formulated with the bare minimum of interactions among all the populations involved in order to highlight the effects of the nonlinearity describing the defense mechanism. A key parameter identified in the purely demographic model, which completely describes its outcomes, is seen here to have an important role also, in that it is dropping below a threshold prevents the disease from invading the environment and causes the healthy prey and predators to coexist via persistent oscillations.

  • articleNo Access

    ROLE OF SPACE IN AN ECO-EPIDEMIC PREDATOR-PREY SYSTEM WITH THE EFFECT OF FEAR AND SELECTIVE PREDATION

    In ecological systems, the fear of predation risk asserts a privilege to the prey species by restricting their exposure to the potential predators. It also imposes costs by constraining the exploration of optimal resources. Additional foods for predators play a pivotal role in the biological conservation programs. The predators have ability to distinguish between the susceptible and infected prey items, and they avoid the latter ones to reduce their fitness cost. A predator-prey model with disease in prey is investigated in this study with an aim to explore the effects of fear factor, additional foods and selective predation on the ecological systems. We also investigate the spatio-temporal model to incorporate the facts that the prey and predator populations perform active movements in the spatial directions for their biological relevance. Both the temporal and spatio-temporal models are analyzed through noteworthy mathematical as well as numerical techniques. Our simulation results show that the level of fear responsible for the reduction in the birth rate of susceptible prey, rate of disease transmission and the selective feeding behavior of predators have potentials to create instability in the ecosystem. In contrast, the level of fear responsible for reduction in the disease prevalence can restore stability in the ecosystem by killing the persistent oscillations. Our eco-epidemic system exhibits chaotic nature if the growth of predators due to additional food sources is very low. We find that the spatio-temporal model demonstrates different spatial patterns of the prey and predator populations in the ecosystem.

  • articleNo Access

    A SEASONALLY FORCED ECO-EPIDEMIC MODEL WITH DISEASE IN PREDATOR AND INCUBATION DELAY

    Our current research is based on the investigation of an eco-epidemiological model that solely includes illness in predators. Predators, both healthy and diseased, are thought to consume prey and breed; however, the offsprings are expected to be vulnerable. To achieve a more realistic and explicit outcome of the existing phenomena correlated with our model system, we consider that the process of disease transmission is mediated by some time lag and the intensity of disease prevalence is seasonally forced. Our simulation results show that the disease dies out for lower intensity of disease prevalence or higher rate of consumption of prey by susceptible predator. The system undergoes subcritical/supercritical Hopf bifurcation as the parameters representing the intensity of disease prevalence, consumption rate of prey by susceptible/infected predator vary. The system exhibits two types of bistabilities: the first one between stable coexistence and oscillating coexistence, and the second one between two oscillatory coexistence cycles. Moreover, we see that with gradual increase in the incubation delay, the system shows transitions from stable focus to limit cycle oscillations to period doubling oscillations to chaotic dynamics. Chaotic dynamics is also observed for the periodic changes in the intensity of disease prevalence if it takes much time for the pathogens to develop sufficiently inside body of the susceptible predators.

  • articleOpen Access

    A FRACTAL FRACTIONAL MODEL FOR CERVICAL CANCER DUE TO HUMAN PAPILLOMAVIRUS INFECTION

    Fractals04 Mar 2021

    In this paper, we have investigated women’s malignant disease, cervical cancer, by constructing the compartmental model. An extended fractal–fractional model is used to study the disease dynamics. The points of equilibria are computed analytically and verified by numerical simulations. The key role of R0 in describing the stability of the model is presented. The sensitivity analysis of R0 for deciding the role of certain parameters altering the disease dynamics is carried out. The numerical simulations of the proposed numerical technique are demonstrated to test the claimed facts.

  • articleNo Access

    Bioboard

      AUSTRALIA – Second-Generation Diagnostic Achieves 98% Accuracy in Detecting Early Stage Ovarian Cancers

      AUSTRALIA – New Center Brings Australian and Chinese Researchers Together to Fight Infectious Diseases

      AUSTRALIA – Co-developing New Treatment Guidelines for Melanoma

      AUSTRALIA – Australia Leads World's First Global Effort to Improve Genetic Disorders Diagnosis

      CHINA – China Bans Illegal Food Additives to Reinforce Food Safety Control

      CHINA – China Steps Up Tighter Inspection in Food Safety

      CHINA – WHO and China to Do More for Chinese with Hearing Impairment

      CHINA – First TCM Drug for Arrhythmia

      CHINA – First Human-Human Transmission of Tick-Borne Disease Reported in China

      CHINA – Bird Flu Found in Chickens in Eastern China

      CHINA – First Bird Flu Death Reported for 2009, No Bird-flu Outbreak

      HONG KONG – Hong Kong Alerts New Bird Flu Outbreak

      INDIA – India Also Confirmed Bird Flu Incidence

      INDIA – India Plans 20 More Biotech Parks for Life Sciences Research

      KOREA – An Economic Share in Medical Tourism Market

      JAPAN – Brain Tissues Made from Stem Cells

      NEW ZEALAND – Newly Merged Research Institute Leverage Greater Synergy

      NEW ZEALAND – Kiwi's Green Plastic Well-Acclaimed in International Awards

      NEW ZEALAND – Sea Sponge Indigenous to NZ Could Reduce Chemo Side Effects

      PHILIPPINES – Ebola-Reston Virus Jumped Species

      SINGAPORE – Human Sewage, the Potential Source of Clean Energy

      SINGAPORE – No More Heart-stopping Incidents for Heart Patients

      SINGAPORE – China Milk Products Get All-Clear from Singapore

      SINGAPORE – Discovery of New Properties in Imidazolium Salts Yield Multi Applications

      SINGAPORE – S'pore Ranked World's Most Prolific for Eye Research Per Capita

      SINGAPORE – Outdoor Sun Reduces Incidence of Myopia in Children

      TAIWAN – University Hospital in Taiwan Collaborates with Neuralstem

      VIETNAM – Return of Bird Flu, Vietnam Runs High Risk of Human Infection

      VIETNAM – Conjoined Twins Successfully Separated

      VIETNAM – Rise in Off-Season Dengue Fever Cases

      NORTH AMERICA – Epilepsy Drugs Prescription to Carry Suicide Risk Warning

      NORTH AMERICA – U.S. Doctors Succeeded Near-total Face Transplant

      NORTH AMERICA – Vaccinating Pacific Girls against Cervical Cancer

      NORTH AMERICA – Manipulating Love and Emotions by Spray

      EUROPE – Cambridge Pips Oxford in Research

      EUROPE – Adapting Car Manufacturing Technology to Produce Synthetic Bone Implants

      EUROPE – Dioxin-tainted Irish Pork Products Recalled

    • articleNo Access

      People Watch

        Chinese Physician Appointed to Lead Clinical Operations of MDS Pharma Services in Asia

        Swiss to Helm Takeda Pharmaceuticals Asia Private Limited as New CEO

        First Asian Honored Prestigious American Award

        I2R's Researcher Selected as One of the Only Two Nokia Visiting Professors for 2009

        International Business Honcho Appointed as New Country CEO for Siemens Singapore

      • articleNo Access

        Research and Findings

          Australian Scientists Reach Breakthrough in Stem Cell Research.

          Breakthrough in Disease Management of Chikungunya Fever by Singapore Researchers.

          MicroRNAs Lead to Formation or Suppression of Tumors? Singapore and US Scientists Share Results.

          Singapore and South Korea to Invent More New Materials.

          Asian Blood Cancer Patients Respond Better with a Lower Drug Dosage.

          Safer Ethical Way to Make Human Stem Cells.

          "Blushing" Response from Alcohol Drinking Signals Increased Cancer Risk Among East Asians.

        • articleNo Access

          Feature

            Interview with Frost & Sullivan — Celebrating Best Practices in Healthcare.

            Interview with InterSystems Corporation — Connecting Applications, Processes and People Intelligently.

            Interview with Philips Healthcare — Excellence in Medical Imaging & Radiology.

            Interview with Roche Diagnostics — Cutting-Edge Clinical Diagnostics.

          • articleNo Access

            Industry Watch

              Benitec MOU with Biomics Biotechnologies China.

              Arkema & Aussie Chemeq Sign Manufacturing Cooperation Agreement.

              AstraZeneca and Mental Health Research Institute in Australia Announce Collaboration to Improve Early Detection of Alzheimer's Disease.

              Avexa Gets CSIRO Investment.

              Living Cell Technologies' Encapsulated Choroid Plexus Cells May Be Used To Treat Hearing Loss.

              Sundia MediTech Acquires Protein Folding Technology.

              Beijing Cancer Hospital Introduces Fast and Precise RapidArc Radiotherapy Cancer Treatments.

              Zydus Cadila and Karo Bio's Research Collaboration has Generated Promising Lead Compounds.

              ICON Acquires Veeda Laboratories Limited.

              Novavax-Cadila to Conduct Swine Flu Clinical Trials.

              Axygen & Astellas form JV to Develop Protein Drugs.

              Rexahn, KRICT to Develop Anti-Cancer Drugs.

              Japan's Largest Pharmaceutical Firm Opens Regional HQ in Singapore.

            • articleNo Access

              Feature

                Ultrasound-Mediated Gene Therapy - Philips and Glygenix Team Up.

                Vietnam Healthcare - The Next Growth Frontier?

                New Ultrasound System Could Lower Number of Biopsies.

              • articleNo Access

                Bioboard

                  AUSTRALIA – New Test Will Help Identify Viral Cattle Disease.

                  AUSTRALIA – Vision CRC Technology to Control Myopia.

                  AUSTRALIA – Living Skin for Burns Victims.

                  AUSTRALIA – IVF Clinic Develops Improved Screening.

                  AUSTRALIA – Glaucoma Affecting 150,000 Australians.

                  AUSTRALIA – Bionic Eye Design to be Unveiled.

                  AUSTRALIA – Australian Scientists in TB Drug Breakthrough.

                  CHINA – China Suffering Diabetes Epidemic: Report.

                  CHINA – Chinese Researchers Discover First Therapeutic Hepatitis B Vaccine in the World.

                  CHINA – In Annual Rite, Chinese Science Showered With Riches.

                  HONG KONG – Swine Flu's Got New Genes On.

                  INDIA – Apollo Hospitals to Conduct Research in Ayurveda.

                  INDIA – Project to Check Heart Disease in Corporates Launched.

                  INDIA – Indian Scientist Develops Low-cost Cancer Detector.

                  INDIA – Conjoined Twins Separated After a 14-hour surgery at Delhi hospital.

                  JAPAN – Genetically Modified Mosquitos may Help Fight Malaria.

                  SINGAPORE – NUHS to Partner Harvard.

                  SINGAPORE – S'pore Team Develops Mobile ECG Machine.

                  SINGAPORE – Novel Method to Produce Precise Medical Images for Detection of Diseases.

                  SINGAPORE – Singapore Got S$1.2 bn Investment in BMS in 2009.

                  SINGAPORE – Singapore and Sweden Institutes Ink Research Collaboration on Environmental Technologies.

                  SINGAPORE – Simple Test for Lung Patients.

                  TAIWAN – Taiwan, Japan Entities Team up on Research.

                  VIETNAM – HCM City Public Hospitals Run Out of Recognized Vaccines.

                  OTHER REGIONS — NORTH AMERICA – Researchers Seek Funding to Study How Climate Change Influenced Human Evolution.

                  OTHER REGIONS — EUROPE – A Blood Test to Detect Breast Cancer.

                • articleNo Access

                  Bioboard

                    AUSTRALIA – Laser Method to Restore Sight an Aussie Miracle.

                    AUSTRALIA – Brain Estrogen Shows Promise as Schizophrenia Treatment.

                    AUSTRALIA – New Blood Test for Newborns to Detect Allergy Risk.

                    AUSTRALIA – UQ Wins $6.5 Million for Groundbreaking Research Projects.

                    CHINA – China: New HIV Model Suggests Killer T Cell for Vaccine.

                    CHINA – 17 Babies Injected with Expired Medicine.

                    CHINA – Substandard Human Rabies Vaccine Recalled.

                    CHINA – China Faces New Health Scare Over 'Bad Vaccines'.

                    INDIA – Artificial Blood Vessels Developed from Jatropha.

                    INDIA – India and Germany to Initiate Joint Research in Oncology, Regenerative Medicine, Neurosciences.

                    INDIA – Indian Scientists Decode TB Bacteria Genome.

                    INDIA – Nearly Half a Million Foreigners Throng India for Cheap Treatment.

                    INDIA – Transgenic Chicken for Therapeutic Use Developed.

                    JAPAN – Japan's Miyazaki Beef Threatened by Foot-and-Mouth Outbreak.

                    SINGAPORE – Number of Flu Cases Near Epidemic Levels.

                    SINGAPORE – $140m Expansion to Increase R&D Space at The Biopolis.

                    SINGAPORE – Singapore Scientists' Zebrafish Model for Parkinson's Disease an Important Step Closer to Drug Development for the Disease.

                    SINGAPORE – Painless, Cheaper Way to Diagnose Bladder Cancer.

                    SINGAPORE – Fujitsu Establishes its First Biomedical Research Laboratory in Singapore.

                    SINGAPORE – A*Star, MRC Grant $4.5m for Six Research Projects.

                    SINGAPORE – Singapore Scientists Exploit p53 to Improve Cancer Treatment.

                    TAIWAN – Taiwan Scientists Identify Keys to Bipolar Disorder.

                    NORTH AMERICA – First Prostrate Cancer Vaccine a Major Breakthrough.

                  • articleNo Access

                    Industry Watch

                      Benitec Limited Granted Hepatitis C RNA Interference Patent in US.

                      HUYA Bioscience International and China Medical City Forge Alliance.

                      Chindex, Fosun Pharma Form Joint Venture.

                      Daiichi Sankyo and Ranbaxy to Integrate New Drug Research and Development System.

                      TAKE Solutions and Reliance Life Sciences Enter Strategic Alliance.

                      Veeda Oncology Announces $8.4 million in New Business.

                      Medicago signs Vaccine MOU with PT Bio Farma.

                      Kyowa Hakko Kirin to Enter Out-licensing Agreement with Biovail.

                      Sosei to Acquire Activus Pharma.

                      Takeda to Expand Operations in South Korea.

                      SymBio and Cephalon Sign License Agreement.

                      Quintiles Announces Clinical Research Partnership with the University Malaya Medical Centre.

                      Roche's New DNA Sequencer Opens Innovation in Genomic Research.

                      Dow Microbial Control Academy Showcases Industrial Leadership and Expertise.

                    • articleNo Access

                      Bioboard

                        AUSTRALIA – New Therapy could Restore Mobility in Stroke Victims.

                        AUSTRALIA – Sugar as Bad as Fat.

                        AUSTRALIA – Scientists Uncover Cancer-fighting "Death" Protein.

                        AUSTRALIA – Shrinking Brain in Dementia Prompts Overeating.

                        AUSTRALIA – New Monitoring System for Mosquito-Borne Disease.

                        AUSTRALIA – Australian Researcher Finds Radical Technique to Save MAS Babies.

                        AUSTRALIA – Austrian Scientists Discover Enzyme Function in Cancer.

                        CHINA – Domestic Dengue Fever Cases Breaks 1,000.

                        CHINA – China Experts Design Gel to Protect Women from HIV.

                        INDIA – India, South Africa to Team up on HIV Vaccine Research.

                        MALAYSIA – Malaysia to use Lab Mosquitoes to Fight Dengue

                        NEW ZEALAND – Plant Derived Foods can Keep us Feeling Full.

                        SINGAPORE – Singapore Hosts First "Decade of the Mind" Conference in Asia and Expands Efforts in Brain & Cognition Research.

                        SINGAPORE – Drugs May Replace Chemo in Leukemia Therapy.

                        SINGAPORE – Singapore Scientists First to Perform Genome-Wide study of Human Stem Cells.

                        SINGAPORE – Singapore Babies in Waste-disease Trial.

                        SINGAPORE – New Technology a Shot in the Arm for Biofuels.

                        SINGAPORE – S$3.7 Billion for Singapore Biomedical Sciences R&D.

                        TAIWAN – Medical Tourism Booms in Taiwan.

                        OTHER REGIONS — EUROPE – Gene that Triggers Human Cancer Identified.

                        OTHER REGIONS — EUROPE – Painfully Potent Pepper.

                        OTHER REGIONS — NORTH AMERICA – 2 Dads and No Mum make 10 Mice.

                      • articleNo Access

                        REVIEW

                          Ocular Toxoplasmosis.

                          International Conference & Exhibition of the Modernization of Chinese Medicine & Health Products (ICMCM) - Annual Pivotal Event for Global Chinese Medicine Industry.