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PIXE technique has been utilized to analyze some obsidian artifacts found in the Southern Platform of the ceremonial center of Lagunillas, Michoacán, México. According to their chemical composition, the provenance of obsidian was established, thereby confirming the commercial routes of the Lagunillas region during Early (A. D. 900-1200) and Late Postclassical periods (A. D. 1200-1523).