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  • articleNo Access

    Research and Findings

      Korean and American Research Institutes Combine Approaches in Analysis of Viral Infectivity

    • articleNo Access

      Commentary and Analysis

        The Elimination of Hospital Acquired Infections: A realistic Goal?

      • articleNo Access

        Industry Watch

          Arana Announces Issuance of Key European Patent for Evibodies.

          Living Cell Technologies Reports Interim Results Showing Sustained Beneft with DIABECELL® Implants for Insulin Dependent Diabetes.

          Topical Microbicide Field Receives Boost with Human Effcacy Result.

          WuXi PharmaTech Honored on the Deloitte Technology Fast 500 Asia Pacifc 2008 List for the Fifth Consecutive Year.

          Syngenta Enters into Research Collaboration with Anhui Academy, China.

          Bayer Schering Pharma to Invest 100 Million Euro in China to Build a Global R&D Center.

          Dow AgroSciences, China National Rice Research Institute Announce Collaboration on Rice Research.

          World's First Robotic Radiosurgery System Introduced at Apollo Hospitals.

          Fortis Ties up with International Oncology.

          Apotex and Intas Biopharma Partner to Develop Biosimilars.

          Abbott Opens New Pediatric Nutrition Manufacturing Facility in Singapore.

          Schering-Plough Opens First R&D Centre in Singapore.

          Hyfux Still Expanding.

          GSK to Commit $1.3 Million to Singapore Institute's Vaccine Development Projects.

          Invida to Market Breakthrough Anti-nausea Patch in Asia Pacifc.

          NUS Partners International Rice Research Institute to Address Global Food Security Challenge.

          Singapore Research Organizations Team up to Advance Drug Discovery Using Brain Tumor Stem Cells.

        • articleNo Access

          Bioboard

            AUSTRALIA – World-Class Cancer Center to be Built in Parkville.

            AUSTRALIA – Cure Found for Devastating Muscle Disease.

            AUSTRALIA – HIV Test to Help Monitor Sufferers.

            AUSTRALIA – Radium Weed Weeds Out Sun Spots, Skin Cancer.

            AUSTRALIA – Kava Safe and Effective in Reducing Anxiety.

            CHINA – CAS Develops New Salt-tolerant Wheat.

            CHINA – Search for Passengers on Flights with Flu Case.

            HONG KONG – Hong Kong Confirms Asia's 1st Swine Flu Case.

            INDIA – Indian Healthcare Market to Grow Despite Slowdown.

            INDIA – WHO Lifts Vaccine Embargo on India.

            JAPAN – Scientists Create World's First Transgenic Monkeys.

            JAPAN – Japan Swine Flu Cases Surge.

            NEW ZEALAND – New Frontiers in Gene Behavior.

            NEW ZEALAND – Innovative Pet Food Research Consortium Launched.

            SINGAPORE – 50 Receive Healthcare Humanity Awards.

            SINGAPORE – No-Go for Swine Flu Parties.

            SINGAPORE – Asia's First Combined Heart and Liver Transplant.

            SINGAPORE – Singapore to Host Conference on Tobacco or Health.

            SINGAPORE – Diabetes Hits Asia's Youth.

            SOUTH KOREA – $14.6 mn for Fight Against New Flu.

            TAIWAN – Flu Vaccine to be Available by End of Year.

            TAIWAN – Mutation in Gene allows Cancer to Spread.

            TAIWAN – Scientists Find Ways to Improve Cancer Drugs.

            TAIWAN – Team Makes Discovery in Search for New Antibiotic.

            TAIWAN – Taiwan Tags Sixteen Countries with Yellow Travel Alert Over Flu.

            TAIWAN – Team Makes Breakthrough in Therapy for Childhood Cancer.

            THAILAND – Thailand Tries to Become Starch-Production Hub.

            THAILAND – Thailand and Taiwan to Begin Biotech Cooperation Plan.

            VIETNAM – US gives Vietnam Protective Bird Flu Equipment.

            OTHER REGIONS — UNITED STATES – Over 52's May Be Better Protected.

          • articleNo Access

            Bioboard

              AUSTRALIA – Hospital Infections Bring Costly Loss in Lost Bed Days.

              CHINA – Novel Mechanism in Chinese Herbs Discovered for Cancer Treatment.

              CHINA – "Dung of the Devil" Plant Roots Point to New Swine Flu Drugs.

              CHINA – New Center at Chinese Academy of Sciences Pushes Life Science Innovation.

              CHINA – A New Function of Insulin Receptor Discovered.

              JAPAN – Researchers Identify Fat-Causing Protein.

              SINGAPORE – Operation Conducted Entirely Through the Navel.

              SINGAPORE – Saliva From Blood-Feeding Bug Could Help Prevent Heart Attacks.

              SINGAPORE – 17 Projects Awarded Grants by A*STAR.

              SINGAPORE – Third Medical School for Singapore.

              SINGAPORE – Singapore's Medical Technology Sector Reports Strong Growth.

              SINGAPORE – Scientists Unlock Secret to Youthful Skin.

              SINGAPORE – Singapore Gears Up for Influenza A (H1N1) Vaccines.

              SINGAPORE – NUS Gets World's Most High-Tech Microscope.

              SINGAPORE – Waseda University Opens First Overseas Biosciences Research Institute in Singapore.

              TAIWAN – Taiwan Makes Headway in New Drug Development.

              TAIWAN – Nutrition Sensor in Plants Pivotal in Understanding Molecular Equilibrium in Human Body.

              VIETNAM – U.S. Provides Aid to Vietnam for Pandemic Preparedness.

              EUROPE – Heart Risks Cut Life Span by 10 Years.

              NORTH AMERICA – Bad Drug Effects in Children from Medicines.

              NORTH AMERICA – Virus Linked to Prostate Cancer Discovered.

              NORTH AMERICA – Will H1N1 Mutate into "Superbug"?

            • articleNo Access

              Feature

                Novel Multiplex PCR Technologies.

                Reducing the Spread of TB in China: New Technology Needed to Turn the Tide.

                Application of Rapid and Accurate Two-Stage Genotyping Strategy in MRSA Nosocomial Infection in Japan.

                Introduction to Luminex®xMAP® Technology and Applications for Biological Analysis in China.

                Label-free Real-time Cell Based Assay System for Evaluating H1N1 Vaccination Success.

              • articleNo Access

                BIOBOARD

                  INDIA – A novel form of gene regulation in bacteria.

                  INDIA – Algal biofuels are no energy panacea.

                  JAPAN – Medical Data Vision enhances the quality of medical care with Actian Vectorwise.

                  SINGAPORE – Singapore heart surgeon to receive honour from The Royal College of Surgeons of Edinburgh.

                  SINGAPORE – ELGA® to deliver innovative water purification at new Singapore General Hospital expansion.

                  AUSTRALIA – Specialised Therapeutics Australia: New drug to fight hospital superbug infection.

                  AUSTRALIA – Group of genes hold the clue in migraine cases.

                  AUSTRALIA – CT scans can triple risk of brain cancer, leukemia.

                  BRAZIL – Science can do more for sustainable development.

                  MIDDLE EAST – Particles and persecution: why we should care about Iranian physicists.

                  EUROPE – Medicyte coordinates EU-funded collaboration on Biomimetic Bioartificial Liver.

                  EUROPE – Selvita and Orion Pharma achieve a research milestone in Alzheimer's Disease Program.

                  EUROPE – Zinforo (ceftaroline fosamil) receives positive CHMP opinion in the European Union for the treatment of patients with serious skin infections or community acquired pneumonia.

                  USA – Vein grown from girl's own stem cells transplanted.

                  USA – Hidden vitamin in milk yields remarkable health benefits - Weill Cornell researchers show tiny vitamin in milk, in high doses, makes mice leaner, faster and stronger.

                  USA – New report finds biotechnology companies are participating in 39% of all projects in development for new medicines and technologies for neglected diseases.

                  USA – TriReme Medical receives FDA clearance for expanded matrix of sizes of Chocolate PTA balloon catheter.

                  USA – New data show investigational compound dapagliflozin demonstrated significant reductions in blood sugar levels when added to sitagliptin in adults with type 2 diabetes at 24 weeks, with results maintained over 48 weeks.

                  USA – Zalicus successfully completes Phase 1 single ascending dose study with Z944, a novel, oral T-Type Calcium Channel Blocker.

                  USA – Study provides clues to clinical trial cost savings.

                • articleNo Access

                  COLUMNS

                    Eliminating MALARIA. Is it Possible?

                    Hand, Foot and Mouth Disease: Symptoms, Prevention and Updates on HFMD.

                  • articleNo Access

                    Eye on China

                      The following topics are under this section:

                      • A general framework for predictive maintenance of manufacturing systems
                      • A remote-controlled smart platform for organ repair
                      • COVID-19 and its genetic relationship with other coronaviruses
                      • East meets West: cancer therapy using acupuncture and electrochemistry
                      • A triple-function bismuth oxochromate photocatalyst
                      • AI enables whole-slide imaging for diagnosis of nasal polyps

                    • chapterNo Access

                      Live Imaging Innate Immune Cell Behavior During Normal Development, Wound Healing and Infection

                      Cells of the innate immune system perform a number for functions that range from clearing apoptotic cell corpses during normal organ development to removing invading pathogens and helping regulate the immune response to infection. Traditional approaches to assessment of these immune cell behaviors have relied upon histological analysis of fixed tissue samples complemented by in vitro functional data. Despite providing significant insights, translating the results from such studies into a multicellular whole animal context is difficult. Recent advances in cell labeling techniques and imaging technologies has given researchers unprecedented ability to directly observe immune cell activities within a live whole animal context. Such live imaging approaches are essential to completely appreciate these activities within their intact normal physiological setting. The zebrafish embryo, with its optical transparency and fully functional innate and adaptive immune systems, represents an ideal system in which to live image innate immune cells. When this is coupled with the relative ease with which specific immune cells can be fluorescently labeled within transgenic reporter lines and the ability to both genetically and chemically interfere with genetic pathways, the zebrafish is emerging as a strong vertebrate platform in which to make novel contributions to understanding immune cell biology. This chapter will discuss how our group and others use live imaging to assess the behavior of myeloid leukocytes during normal development and in response to different inflammatory stimuli, including wounding and pathogenic challenge.