Narrow Results

Health Research at Monash University Boosted by Grants.

New Laser Research Facility in Australia.

Analysis of the Insulin Market in China.

GM Seed Piracy Widespread in Gujarat.

Tamil Nadu Decides to Build Bio-Fertilizers Bank.

Korean Shares of China’s Medical Industry.

Biotech Corn to Meet Domestic Demand.

China Takes Lead in Export of Traditional Medicines in the World.

Novo Nordisk’s Strategic Capture of China’s Insulin Market.

Intellectual Property Strategies in Security and Privacy.

Aspect Medical Systems and Brain Resource Company Partners in MCI Study.

Mesoblast and Cordis Collaborate on Adult Stem Cell Heart Trial.

Apollo Life Sciences Begins Sale of Human Cell-Expressed Proteins Globally.

Workhardt Introduces Hepatitis A Vaccine into Indian Market.

Transgene Biotek Develops Oral Delivery of Insulin and Hepatitis B Vaacine.

Japan's Bioventures Today - Peruseus Proteomics Inc.

AUSTRALIA – Mosquito Parasite Could Control Dengue

CHINA – China has Twice the Global Average of Drug-Resistant Tuberculosis

CHINA – 80 000 Antibiotics Abuse-related Deaths Annually

CHINA – Bird Flu Found in Chicken from China

CHINA – China on Alert following Bird Flu Death

CHINA – Chinese Dairies to Compensate Tainted Milk Victims' Families

CHINA – New Insulin Resistance Tricks Found

CHINA – World's First Plant Chromosome Atlas

CHINA – Project Launched to Study Structure of Proteins

CHINA – Fake Diabetes Drug Linked to Two Deaths

CHINA – Birth Defects Rising in Polluted China

INDIA – India Culls Poultry in Darjeeling After Bird Flu

INDIA – India Introduces Second-Line Anti-retroviral Treatment in Eight States

INDIA – Indian Medical Tourism to Reach US$1.9 billion by 2015

INDIA – Canadian and Indian Ministers Sign Pact on Agriculture Cooperation

INDIA – 6000 year-old Rice Species Discovered in Meghalaya

INDIA – Genetics to Help Conserve Rare Bird Species

JAPAN – Coating the Protein Enhances Disease-fighting Capability

JAPAN – Scientists Isolate Genes that Made 1918 Flu Lethal

JAPAN – Researchers in Japan Develop All-round Flu Vaccine

PHILIPPINES – Ebola Reston Virus Found in Filipino Farm Worker

SINGAPORE – New Method to Create iPS Cells

SINGAPORE – Ray of Hope for Liver Cancer Sufferers

SINGAPORE – Bacteria Improve Energy and Cost Efficiency in Water Treatment

TAIWAN – Secrets of “Speciation” Gene Unravelled

TAIWAN – Initial Breakthrough in Poultry Vaccine Development

TAIWAN – Taiwan Gains Direct Access to WHO

VIETNAM – Doctors Report First Drug Hypersensitivity Syndrome

VIETNAM – Public Advised Serious Caution Against Bird Flu

NORTH AMERICA – Kids of Pregnant Drinking Mums will Like Booze

NORTH AMERICA – High Functional Diversity in Mycobacterium Tuberculosis Driven By Genetic Drift And Human Demography

NORTH AMERICA – Newly Discovered Tuberculosis Protein May Help Explain Bacterium's Resilience

NORTH AMERICA – U.S. Patent For Diagnostic Technology Awarded To URMC, Lighthouse Biosciences

EUROPE – Structure Mediating Spread of Antibiotic Resistance Discovered

EUROPE – New EU Pesticide Regulations Could Undermine Battle against Malaria

EUROPE – iPill – The Smart Drug Delivery that can “Call” the Doctor

EUROPE – What Drives Locusts to Swarm

Novation, Cancer Therapeutics to Jointly Develop Cancer Therapies.

Mesoblast Announces Positive Results in Bone Marrow Transplant Trial.

Mingyuan Medicare Announces Collaboration on Major Infectious Diseases Detecting Platform.

DHL Launches first Life Science & Healthcare Competence Centre in Shanghai.

Abraxis Bioscience Launches ABRAXANE for Metastatic Breast Cancer.

GSK Enters Flu-Vax JV in China.

Biocon Launches Long Lasting Basal Insulin for Type 1 & Type 2 Diabetics.

Kemwell to build Biopharmaceutical Manufacturing Facility in India in Collaboration with Boehringer Ingelheim, Germany.

Hemispherx, Biken Expands Production Capacity for Swine Flu Vaccines.

D-SIMLAB Awarded S$500,000 Grant under SPRING Singapore's Technology.

GlaxoSmithKline Opens $600million Vaccine Plant.

Agilent Technologies Opens New Life Sciences Manufacturing Facility in Singapore.

Six Doctors Receive Clinician Scientist Awards.

AUSTRALIA – Silk Microchip for Rapid Medical Testing.

AUSTRALIA – New Insulin that Won't Need Cooling -a Boon for Diabetics.

AUSTRALIA – Scientists Developing Synthetic Skin.

AUSTRALIA – Australian Scientists' Lung Breakthrough.

AUSTRALIA – Aussie Scientists Find the 'Lazy' Eye Gene.

AUSTRALIA – Researchers Probe New Malaria Treatment.

AUSTRALIA – Cancer Treatment Pioneered in Melbourne being Hailed as a Global Lifesaver.

CHINA – Plastic Surgery Increasingly Popular Among Seniors.

CHINA – Scientists Develop New Nanotech Approach.

INDIA – India to Promote Biotech R&D Activities in NE States.

INDIA – India to Set Up Academy of Scientific and Innovative Research.

INDIA – Rare Ear Surgery Performed on Dubai Boy.

INDIA – Global Biotech Firms Seek Partnerships in India for Bigger Gains.

SINGAPORE – GSK, EDB to Fund S$50 mn to Support Manufacturing in Singapore.

SINGAPORE – A*STAR, UK Unite to Fight Infectious Disease.

SINGAPORE – New Treatment Option for Women Who Suffer from Incontinence.

THAILAND – Thailand Builds Capabilities in Nanotech Research.

OTHER REGIONS — NORTH AMERICA – Scientists Predict Lifespan.

OTHER REGIONS — NEW ZEALAND – Orthopedic Implants Made from Shell.

Phylogica Commences Antimicrobial Peptide Discovery under Agreement with MedImmune.

Leadtec Systems Australia to Acquire Mimotopes.

Sirnaomics Seals Deal for Development of RNAi Therapeutics in China.

Simcere and Bristol-Myers Squibb Enter Innovative Partnership to Develop Early-Stage Oncology Compound.

Pfizer, Biocon in $350 Million Insulin Pact.

Bharat Biotech Announces Launch of 'HNVAC™' India's First Cell-Culture H1N1 Swine Flu Vaccine.

Cipla Launches the World's First Generic Pirfenidone in India, Giving Hope to Sufferers of IPF (Idiopathic Pulmonary Fibrosis).

Eisai and FORMA Therapeutics Enter into Broad Drug Discovery Collaboration.

Philips and Atom Medical Corporation Announce Strategic Alliance to Provide a Complete Neonatal and Perinatal Offering.

CiRA and France-based Cellectis Enter Collaboration.

Immunovaccine Signs Research Agreement with OncoTherapy Science to Advance Potential Cancer Vaccine.

Glycos Biotechnologies Enters Definitive Agreement with Malaysian Bio-XCell.

Biocon Plans to Invest $161m in Malaysia to Set Up R&D Unit.

Coin-sized Micro-needles Patch to deliver Insulin: An innovation by Shanghai University Scientists

Stem Cells Help Researchers Study The Effects of Pollution on Human Health

A Novel and Robust Muscle Activity Onset Detection Technique by Using an Unsupervised Electromyogram Learning Framework

Early Modern Humans and Neanderthals were close bedfellows

FANCD2 and REV1 Cooperate in the Protection of Nascent DNA Strands in Response to Replication Stress

Spiders' Foraging Strategies Have Cascading Effects on Litter Decomposition Rates

Yingli Announces Sale of 18.8 MW Solar Power Plant in the UK to NextEnergy Solar Fund

China's Award Winning Desertification Control in Kubiqi Desert

Earthquake Early Warning System for Nepal

Mechanical Coupling Mechanism of a Mechanical Force-sensing Channel Protein Discovered by IBP Scientists

Jiahui International Hospital and Brigham and Women's Hospital to Co-Develop Women's Health Center of Excellence in Shanghai

Big Grain1: The ‘Mr. BIG’ for Crops to Grow Bigger by Regulating Auxin Transport in Rice

When there is no Queen in the house, Asian Hive Bees Avoid Risky Foraging for Reproduction

UNICEF HK joins hands with Government to help Mothers sustain Breastfeeding

Fresenius Medical Care Springs into Action after Deadly Tianjin Explosion

SINGAPORE – A*STAR Scientists Reveal How Stem Cells Defend Against Viruses: New Insights to the Mechanisms bring Broad Implications to Stem Cell Therapy and Disease Diagnosis

SINGAPORE – Singtel - Singapore Cancer Society Race against Cancer 2015

SINGAPORE – NCCS and IMCB to Collaborate on Research for New Treatments to Benefit Cancer Patients

SINGAPORE – MerLion’s Finafloxacin Shown to be More Efficacious than Ciprofloxacin in the Treatment of Complicated Urinary Tract Infections

TAIWAN AND UNITED STATES – Professor Yuk-ling Yung Receives Gerard P. Kuiper Prize

SWEDEN – New Data Confirm Tresiba^® U200 Delivers Significantly Lower Rates of Confirmed Hypoglycaemia versus Insulin Glargine U100

UNITED KINGDOM – Using Ultrasound to Clean Medical Instruments

THE NETHERLANDS & UNITED STATES – Philips and Dutch Radboud University Medical Centre Introduce First Diabetes Prototype App with Integrated Online Community to Empower Patients and Enhance Continuity of Care

UNITED STATES – New Clinical Architecture Content Cloud Establishes Reliable Single Source for Terminology Updates, Makes It Easier to Keep Healthcare Systems Up-to-Date

UNITED STATES – Genomic Analysis for All Cancer Patients

UNITED STATES – Birds That Eat at Feeders Are More Likely to Get Sick, Spread Disease, International Research Team Says

Understanding Diabetes

Prediabetes: The Gap between the Onset of Disease and Initiation of Treatment.

Diabetes: A Dietitian’s Perspective.

Use of Modelling for Better Diabetes Care.

No More Highs and Lows with Toujeo®: A New and Improved Insulin Injection.

ATOZET® a New Combination Treatment Option for High-Risk Patients to Lower LDL Cholesterol, is Now Approved in Singapore.

ASEAN+ Rare Disease Network Established.

Luye Medical Joins Forces with OncoCare To Expand Its Integrated Healthcare Services Platform for Their Patients.

NUS Pharmacy Team Develops Online “Calculator” to Predict Risk of Early Hospital Readmission.

The Bare Essentials: Ensuring Affordable Access to Insulin.

AstraZeneca’s CVD-REAL Study Shows SGLT-2 Inhibitors Significantly Reduced Death and Hospitalisations for Heart Failure Versus Other Type-2 Diabetes Medicines.

SCIENCE CHINA Life Sciences English Edition Publishes Domestic Type 2 Diabetes Research Findings.

Omega-3 Therapy May Help Reverse Type 1 Diabetes.

New Plastic-Eating Fungus May Solve Garbage Problem.

Chinese Researchers Reveal How Cells Prevent Viral Invasion.

Scientists Unlock TCM Drug’s Role in Weight Loss.

Medical Reforms in Beijing.

East China’s Anhui Province Innovates Advanced Technology.

DeltaHealth and Harvard Global Health Institute Hold Symposium.

HONG KONG News – HKSTP Welcomes Maz World to Hong Kong’s Vibrant Ecosystem to Commercialise Revolutionary Ostrich Antibody Technology from Japan

Mab-Venture Biopharma & Thermo Fisher Establish Asia Pacific’s First “SmartFactory” for Antibody Drugs.

Venus Medtech’s TAVR Device Is Approved By CFDA, Creating A New Era of Interventional Cardiology in China.

Key Diabetes Receptor Structure Determined by International Collaboration.

China Sets Up National Lab Developing Brain-Like AI Technology.

Chinese Scientists Realize On-site Drug Detection.

Scientists Map Single-Copy HIV-1 Provirus Loci in Human Chromosomes in Live Host Cells.

Gene Variant Explains Differences in Blood Fatty Acid Levels.

Scientists Illustrate How Host Cell Responds to Zika Virus Infection.

Hong Kong News – Uni-Bio Science Launches Best-in-Class Oral Anti-Diabetic Drug Mitiglinide Branded “博康泰^®”(Bokangtai).

Keep the weight off, keep diabetes at bay

Tackling obesity in ASEAN

Insulin resistance as well as insulin deficiency are said to be principal to the development of type 2 diabetes mellitus (T2Dm). Heme has also been suggested to play an important role in the disease etiology since many of the heme deficiency symptoms constitute the common pathological features of T2Dm. Besides, iron overload, higher heme iron intake and transfusion requiring diseases are associated with a higher risk of T2Dm development. In this study the interaction between these two key components i.e. heme and insulin has been studied spectroscopically under different conditions which include the effect of excess peptide as well as increasing pH. The resultant heme-insulin complexes in their reduced state are found to produce very little partially reduced oxygen species (PROS) on getting oxidized by molecular oxygen. The interaction between insulin and previously reported T2Dm relevant heme-amylin complex were also examined using absorption and resonance Raman spectroscopy. The corresponding data suggest that insulin sequesters heme from heme-amylin to form the much less cytotoxic heme-insulin.

In this study, the ability of salvianolic acids A, B, C, F, G and calix[$n$]arenes ($n=4$, 5, 6 and 8) with different upper rims in the inhibition of insulin amyloid fibril formation was studied using molecular docking. The results were analyzed from a molecular point of view. All of the considering ligands interacted with significant residues of insulin, which had a crucial role in the process of insulin fibrillation. The interactions among the ligands and insulin residues could be done through hydrogen bonding and hydrophobic interactions with good binding affinity. So, these ligands could prevent the formation of the insulin fibril. The good consistency of the docking results of $P$-sulfonatocalix[4]arene and $P$-sulfonatocalix[6]arene with the experimental results in the previous literature represented the capacity of the current theoretical method to supplement and interpret experimental findings. Also, in this study, salvianolic acids A, C, F and G were suggested as new inhibitors of the insulin amyloid fibril.