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Dunkle Materie (DM) came from unexpected cosmological observations. Nowadays within our solar system, diverse observations also defy conventional explanations, like the main physical process(es) underlying the heating of the different solar atmospheric layers. Streaming DM offers a viable common scenario following gravitational focusing by the solar system bodies. This fits as the underlying process behind the solar cycle, which was the first signature suggesting a planetary dependency. The challenge, since 1859, is to find a remote planetary impact, beyond the extremely feeble planetary tidal force. We stress the possible involvement of an external impact by some overlooked “streaming invisible matter”, which reconciles all investigated mysterious observations mimicking a not extant remote planetary force. Unexpected planetary relationships exist for both the dynamic Sun and Earth, reflecting multiple signatures for streaming DM. The local reasoning à la Zwicky is also suggestive for searches including puzzling biomedical phenomena. Favorite DM candidates are anti-quark-nuggets, magnetic monopoles, dark photons, or the composite “pearls”. Then, anomalies within the solar system are the manifestation of the dark Universe. The tentative streaming DM scenario enhances spatiotemporally the DM flux favouring conditions for direct DM detection or extracting energy from the not-so-invisible as anticipated dark sector.

We present signature for planetary correlations following an analysis of monthly melanoma rates in USA for the period 1973–2011. Apart from seasonal observations, to the best of our knowledge, a planetary relationship in medicine is observed for the first time. The statistical significance is well above 5$\sigma$, while various crosschecks make systematics highly improbable as the cause. The observed planetary dependence in physics was suggestive for this investigation, which extends the otherwise unexpected planetary connection. Thus, streaming invisible matter from the dark sector, whose flux can be occasionally enhanced towards the Earth via planetary gravitational focusing, and, even much stronger by the Sun, it may be the explanation for 1–10% of melanoma diagnoses. The derived shortest melanoma periodicity of about 87.5 days points in its own right at a short latency period of about few months. Contrariwise, the present findings strengthen the previous physics claim of streams of invisible matter.

In [Biophys. Rev. Lett. 14, 1–9 (2018), arXiv: 1812.02482], Socas-Navarro (SN) provided multiple confirmation of the claimed $\sim$88 days melanoma periodicity [K. Zioutas and E. Valachovic, Biophys. Rev. Lett.13, 75 (2018), https://doi.org/10.1142/S179304801850008X, https://doi.org/10.1016/j.dark.2017.06.001.] (which remarkably coincides with the orbital period of Mercury). This greatly strengthens the observation by Zioutas and Valachovic (ZV). Here, we comment on the work by SN, because it objects the interpretation of the observation by ZV. Note that SN objection is based on serious assumptions, which were explicitly excluded by ZV. Further, the conclusion made with a sub-set of data (4%) is statistically not significant to dispute ZV. On the contrary, since the same periodicity appears also in other eight major cancer types, we consider it as a global oscillatory behavior of cancer. At this stage, such a rather ubiquitous cancer periodicity makes any discussion of a small subset of data at least secondarily. Further, we show here that the $\sim$88 days Melanoma periodicity is not related to solar activity. Planetary lensing of streaming low speed invisible massive particles remains the only viable explanation, as it has been introduced previously with a number of physics observations [S. Bertolucci, K. Zioutas, S. Hofmann and M. Maroudas, Phys. Dark Univ.17, 13 (2017), https://doi.org/10.1016/j.dark.2017.06.001.]. We also show that planetary lensing of low speed particles cannot be considered in isolation, because of the dominating Sun’s gravity, at least for the inner planets. Interestingly, gravitational lensing/deflection favors low speed particles.

This report addresses the time dependence of normal biomedical processes. The conception rate in humans shows relationships that strikingly coincide with planetary periodicities like the orbital period of Jupiter, the 11 years solar cycle and the 237 days Jupiter–Venus synod, and the combined dependence on Jupiter with Mars’ orbital position. The birth rates are used as conception surrogates based on a data set available from the Minnesota Department of Health. The statistical significance of each independent analysis (far) exceeds 5$\sigma$. This result cannot be explained with known science. As with other observations in Physics and Medicine (i.e., melanoma), tentatively the only viable explanation we have is the otherwise invisible streaming matter from the dark Universe we live in. The favored dark matter scenario involves streams or clusters as opposed to an isotropic dark sector. The dark Universe scenario has been the driving idea for this type of work. The high sensitivity of living matter to the tiniest external impact might help identify the nature of the dark matter particles, a major problem in all physics since the 1930s. This work is a model for evaluating other biological processes and mutation rates.