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Tendon-driven continuum robot kinematic models are frequently computationally expensive, inaccurate due to unmodeled effects, or both. In particular, unmodeled effects produce uncertainties that arise during the robot’s operation that lead to variability in the resulting geometry. We propose a novel solution to these issues through the development of a Gaussian mixture kinematic model. We train a mixture density network to output a Gaussian mixture model representation of the robot geometry given the current tendon displacements. This model computes a probability distribution that is more representative of the true distribution of geometries at a given configuration than a model that outputs a single geometry, while also reducing the computation time. We demonstrate uses of this model through both a trajectory optimization method that explicitly reasons about the workspace uncertainty to minimize the probability of collision and an inverse kinematics method that maximizes the likelihood of occupying a desired geometry.