Narrow Results

This work is concerned about multiscale models of compact bone. We focus on the lacuna–canalicular system. The interstitial fluid and the ions in it are regarded as solvent and others are treated as solute. The system has the characteristic of solvation process as well as non-equilibrium dynamics. The differential geometry theory of surfaces is adopted. We use this theory to separate the macroscopic domain of solvent from the microscopic domain of solute. We also use it to couple continuum and discrete descriptions. The energy functionals are constructed and then the variational principle is applied to the energy functionals so as to derive desirable governing equations. We consider both long-range polar interactions and short-range nonpolar interactions. The solution of governing equations leads to the minimization of the total energy.