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This work investigated knowledge of garden egg farmers’ safe usage and application of pesticides in Southeast, Nigeria. The study adopted a mixed method approach involving structured interview and focus group discussion. The mean and percentage responses were obtained and ranked in ascending order of magnitude. The result shows that in a scale of 1-5, knowledge of reading labels on pesticide container with a mean rank of 1.482 is the lowest followed by safety storage with mean rank of 1.529 while the highest is the determination of the size of application area with a mean rank of 4.661. The key implication of the findings of this study in practice is that if garden egg farmers do not indulge in reading nor consider their safety and that of their family members, many people will be affected with pesticide residue. It is recommended that librarians will adequately educate the garden egg farmers on safe usage of pesticide and equally organise reading programmes for them to fulfil the philosophy and practice of librarianship.